SLC25A11: A Protein Involved in Cell Membrane Transport and Cellular Processes
SLC25A11: A Protein Involved in Cell Membrane Transport and Cellular Processes
SLC25A11 (SLC20A4) is a protein that is expressed in various tissues throughout the body. It is a member of the solute carrier family 25 (SLC25) and is characterized by its ability to transport a variety of molecules, including small molecules, ions, and proteins across cell membranes. SLC25A11 is also known as SLC20A4 because it belongs to the subfamily 20 (A4) of the SLC25 family.
SLC25A11 is expressed in many different tissues, including the brain, heart, liver, and kidneys. It is also found in the placenta and in the urine. SLC25A11 is involved in the transport of various molecules across cell membranes, including small molecules, ions, and proteins. It is also involved in the regulation of various cellular processes, including the transport of nutrients and the elimination of waste products.
SLC25A11 has been shown to be involved in a variety of diseases and conditions, including cancer, neurodegenerative diseases, and kidney disease. SLC25A11 has also been shown to be a potential drug target, with researchers investigating its potential as a therapeutic agent for a variety of conditions.
One of the main functions of SLC25A11 is its role in the transport of nutrients across cell membranes. It is able to transport a wide variety of molecules, including glucose, insulin, and various ions, such as calcium, magnesium, and potassium. SLC25A11 is also involved in the regulation of the amount of nutrients that are allowed to enter cells, helping to maintain homeostasis within the body.
In addition to its role in nutrient transport, SLC25A11 is also involved in the regulation of the elimination of waste products. It is able to transport proteins and other molecules across cell membranes, allowing them to be eliminated from the body. This helps to maintain a healthy balance of waste products within the body and helps to prevent the buildup of harmful substances that can cause disease.
SLC25A11 is also involved in the regulation of cellular processes that are important for overall health and function. It is involved in the transport of nutrients and oxygen to cells, as well as the transport of waste products away from cells. It is also involved in the regulation of cellular signaling, helping to maintain the balance of signaling molecules within the body.
In addition to its role in nutrient transport and waste elimination, SLC25A11 is also involved in the regulation of cellular processes that are important for overall health and function. It is involved in the transport of nutrients and oxygen to cells, as well as the transport of waste products away from cells. It is also involved in the regulation of cellular signaling, helping to maintain the balance of signaling molecules within the body.
SLC25A11 is also involved in the regulation of the formation of new blood vessels. It is able to transport nutrients and oxygen to the formation site of new blood vessels, helping to support their growth and development. This is important for maintaining blood flow to the body's various tissues and for supporting the growth and development of new blood vessels.
In conclusion, SLC25A11 (SLC20A4) is a protein that is expressed in various tissues throughout the body and is involved in the transport of various molecules across cell membranes. It is also involved in the regulation of various cellular processes, including nutrient transport, waste elimination, and cellular signaling. SLC25A11 is a potential drug target and has been shown to be involved in a variety of diseases and conditions. Further research is needed to fully understand the role of SLC25A11 in
Protein Name: Solute Carrier Family 25 Member 11
Functions: Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate. Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity. Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity). Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed:21448454). Involved in the regulation of apoptosis (By similarity). Helps protect from cytotoxic-induced apoptosis by modulating glutathione levels in mitochondria (By similarity)
More Common Targets
SLC25A12 | SLC25A13 | SLC25A14 | SLC25A15 | SLC25A16 | SLC25A17 | SLC25A18 | SLC25A19 | SLC25A2 | SLC25A20 | SLC25A21 | SLC25A21-AS1 | SLC25A22 | SLC25A23 | SLC25A24 | SLC25A24P1 | SLC25A25 | SLC25A25-AS1 | SLC25A26 | SLC25A27 | SLC25A28 | SLC25A29 | SLC25A3 | SLC25A30 | SLC25A31 | SLC25A32 | SLC25A33 | SLC25A34 | SLC25A35 | SLC25A36 | SLC25A37 | SLC25A38 | SLC25A38P1 | SLC25A39 | SLC25A3P1 | SLC25A4 | SLC25A40 | SLC25A41 | SLC25A42 | SLC25A43 | SLC25A44 | SLC25A45 | SLC25A46 | SLC25A47 | SLC25A47P1 | SLC25A48 | SLC25A48-AS1 | SLC25A5 | SLC25A5-AS1 | SLC25A51 | SLC25A51P1 | SLC25A52 | SLC25A53 | SLC25A5P1 | SLC25A6 | SLC26A1 | SLC26A10P | SLC26A11 | SLC26A2 | SLC26A3 | SLC26A4 | SLC26A4-AS1 | SLC26A5 | SLC26A5-AS1 | SLC26A6 | SLC26A7 | SLC26A8 | SLC26A9 | SLC26A9-AS1 | SLC27A1 | SLC27A2 | SLC27A3 | SLC27A4 | SLC27A5 | SLC27A6 | SLC28A1 | SLC28A2 | SLC28A2-AS1 | SLC28A3 | SLC28A3-AS1 | SLC29A1 | SLC29A2 | SLC29A3 | SLC29A4 | SLC2A1 | SLC2A1-DT | SLC2A10 | SLC2A11 | SLC2A12 | SLC2A13 | SLC2A14 | SLC2A2 | SLC2A3 | SLC2A3P1 | SLC2A4 | SLC2A4RG | SLC2A5 | SLC2A6 | SLC2A7 | SLC2A8