SLC25A27: A Protein Regulating Blood Pressure and Other Processes
SLC25A27: A Protein Regulating Blood Pressure and Other Processes
SLC25A27 (RP11-446F17.2) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the SLC25 family of transport proteins, which are known for their ability to transport a wide variety of molecules across cell membranes. SLC25A27 has been shown to play a role in the regulation of blood pressure, and is often used as a drug target or biomarker for various diseases.
The SLC25 family of transport proteins consists of four subfamilies: SLC25A, SLC25B, SLC25C, and SLC25D. SLC25A27 is a member of the SLC25A subfamily, and is responsible for transporting the protein SLC25A27 across cell membranes. SLC25A27 is a 27 kDa protein that consists of 214 amino acid residues. It has a calculated pI of 10.9, which means that it is highly susceptible to changes in pH levels.
SLC25A27 has been shown to play a role in the regulation of blood pressure. High levels of SLC25A27 have been associated with an increased risk of hypertension, while low levels of SLC25A27 have been associated with a decreased risk of hypertension. This is because SLC25A27 is involved in the regulation of the volume of blood vessels, which is a critical factor in the regulation of blood pressure.
SLC25A27 has also been shown to play a role in the regulation of various other physiological processes in the body. For example, SLC25A27 has been shown to be involved in the regulation of inflammation, insulin sensitivity, and the production of reactive oxygen species (ROS).
SLC25A27 has also been shown to be a potential drug target or biomarker for various diseases. For example, studies have shown that SLC25A27 is downregulated in individuals with hypertension, and that inhibition of SLC25A27 has been shown to be effective in reducing blood pressure in these individuals. Additionally, SLC25A27 has been shown to be involved in the regulation of various signaling pathways, and may be a potential target for small molecules that can modulate these pathways.
In conclusion, SLC25A27 (RP11-446F17.2) is a protein that is involved in the regulation of various physiological processes in the body. It is a member of the SLC25 family of transport proteins, and has been shown to play a role in the regulation of blood pressure, as well as inflammation, insulin sensitivity, and other processes. As a result, SLC25A27 is often used as a drug target or biomarker for various diseases. Further research is needed to fully understand the role of SLC25A27 in the regulation of physiological processes and its potential as a drug.
Protein Name: Solute Carrier Family 25 Member 27
Functions: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. May play a role in thermoregulatory heat production and metabolism in brain
More Common Targets
SLC25A28 | SLC25A29 | SLC25A3 | SLC25A30 | SLC25A31 | SLC25A32 | SLC25A33 | SLC25A34 | SLC25A35 | SLC25A36 | SLC25A37 | SLC25A38 | SLC25A38P1 | SLC25A39 | SLC25A3P1 | SLC25A4 | SLC25A40 | SLC25A41 | SLC25A42 | SLC25A43 | SLC25A44 | SLC25A45 | SLC25A46 | SLC25A47 | SLC25A47P1 | SLC25A48 | SLC25A48-AS1 | SLC25A5 | SLC25A5-AS1 | SLC25A51 | SLC25A51P1 | SLC25A52 | SLC25A53 | SLC25A5P1 | SLC25A6 | SLC26A1 | SLC26A10P | SLC26A11 | SLC26A2 | SLC26A3 | SLC26A4 | SLC26A4-AS1 | SLC26A5 | SLC26A5-AS1 | SLC26A6 | SLC26A7 | SLC26A8 | SLC26A9 | SLC26A9-AS1 | SLC27A1 | SLC27A2 | SLC27A3 | SLC27A4 | SLC27A5 | SLC27A6 | SLC28A1 | SLC28A2 | SLC28A2-AS1 | SLC28A3 | SLC28A3-AS1 | SLC29A1 | SLC29A2 | SLC29A3 | SLC29A4 | SLC2A1 | SLC2A1-DT | SLC2A10 | SLC2A11 | SLC2A12 | SLC2A13 | SLC2A14 | SLC2A2 | SLC2A3 | SLC2A3P1 | SLC2A4 | SLC2A4RG | SLC2A5 | SLC2A6 | SLC2A7 | SLC2A8 | SLC2A9 | SLC2A9-AS1 | SLC30A1 | SLC30A10 | SLC30A2 | SLC30A3 | SLC30A4 | SLC30A4-AS1 | SLC30A5 | SLC30A6 | SLC30A7 | SLC30A8 | SLC30A9 | SLC31A1 | SLC31A2 | SLC32A1 | SLC33A1 | SLC34A1 | SLC34A2 | SLC34A3