SLC30A2: A Potential Drug Target for Neurological Disorders (G7780)

Target Name: SLC30A2

NCBI ID: G7780

SLC30A2: A Potential Drug Target for Neurological Disorders

SLC30A2 (OTTHUMP00000008699) is a protein that is expressed in the brain and is known for its role in the regulation of cell survival and proliferation. It is a member of the SLC family of transport proteins, which are known for their ability to transport a wide variety of molecules across cell membranes. SLC30A2 has been shown to play a role in the regulation of neuronal excitability and is therefore considered a potential drug target (or biomarker).

The role of SLC30A2 in the nervous system is to control neuronal excitability by regulating the open state of ion channels. In neurons, ion channels play a very important role. They allow ions to flow inside and outside the cell, thereby maintaining the normal function of neurons. SLC30A2 controls the activity of ion channels by regulating the open state of ion channels, thereby affecting the excitability of neurons.

The role of SLC30A2 in neurons also involves cell proliferation and survival. Neurons are one of the most important cell types in the nervous system, and their proliferation and survival are crucial to the normal function of the nervous system. SLC30A2 affects the proliferation and survival of neurons by regulating the open state of ion channels, thereby playing a crucial role in the normal function of the nervous system.

The role of SLC30A2 in the nervous system is also closely related to the occurrence and development of diseases. Many neurological diseases, such as neurodegenerative diseases, are related to abnormal open states of ion channels. SLC30A2 affects the excitability and proliferation of neurons by regulating the open state of ion channels, and is thus closely related to the occurrence and development of these diseases.

SLC30A2 is a very important protein. Its role in the nervous system involves the open state of ion channels, cell proliferation and survival, and the occurrence and development of diseases. Therefore, SLC30A2 is a potential drug target (or biomarker) and can be used as a potential drug for the treatment of neurological diseases.

Protein Name: Solute Carrier Family 30 Member 2

Functions: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity (PubMed:21289295, PubMed:25808614, PubMed:25657003, PubMed:30893306, PubMed:17065149, PubMed:22733820). Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells (PubMed:19496757). By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution (PubMed:25808614)

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