SLC37A1: A Drug Target / Disease Biomarker (G54020)

Target Name: SLC37A1

NCBI ID: G54020

SLC37A1: A Drug Target / Disease Biomarker

SLC37A1 is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including diabetes, heart disease, and cancer. The gene is located on chromosome 12 and encodes a protein known as solute carrier family 37 member A1 (SLC37A1).

SLC37A1 is a transmembrane protein that is involved in the transport of different types of molecules across the cell membrane. The protein has been shown to play a role in the regulation of ion and water transport in various body tissues and organs, including the brain, heart, kidneys, and liver.

One of the key functions of SLC37A1 is its role in the regulation of intracellular fluid (ICF) homeostasis. ICF is a critical component of the body's extracellular matrix and helps to maintain the proper structure and function of various tissues and organs. SLC37A1 is shown to play a key role in the regulation of ICF levels and has been shown to be involved in the development and maintenance of various diseases, including cancer.

In addition to its role in ICF homeostasis, SLC37A1 is also involved in the regulation of pain perception and neurotransmitter release. The protein has been shown to play a role in the regulation of neurotransmitter release from neurons and has been shown to be involved in the development of various neurological disorders, including pain perception and depression.

SLC37A1 has also been shown to play a role in the regulation of cell survival and proliferation. The protein has been shown to play a role in the regulation of cell cycle progression and has been shown to be involved in the development and progression of various cancers, including breast and colorectal cancer.

In conclusion, SLC37A1 is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases. Further research is needed to fully understand the role of SLC37A1 in the regulation of ICF, pain perception, neurotransmitter release, cell survival and proliferation, and other processes in the body.

Protein Name: Solute Carrier Family 37 Member 1

Functions: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels

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