SLC39A3: A Potential Drug Target and Biomarker (G29985)

Target Name: SLC39A3

NCBI ID: G29985

SLC39A3: A Potential Drug Target and Biomarker

SLC39A3 (zrt- and Irt-like protein 3) is a protein that is expressed in various tissues throughout the body. It is a member of the SLC family of transmembrane proteins, which are known for their ability to transport various molecules across cell membranes. One of the unique features of SLC39A3 is its ability to interact with a variety of different molecules, including drugs and other proteins. This interactivity makes it an attractive candidate for drug targeting and as a biomarker for various diseases.

The SLC39A3 protein is composed of 114 amino acid residues and has a calculated molecular weight of 13.9 kDa. It is expressed in a variety of tissues, including the brain, heart, skeletal muscles, and tissues of the urinary tract. SLC39A3 is also known to be involved in various signaling pathways, including the regulation of ion channels and the transport of molecules across cell membranes.

One of the unique features of SLC39A3 is its ability to interact with a variety of different molecules. It has been shown to interact with a variety of different proteins, including the protein known as TrkB. TrkB is a G protein-coupled receptor that is involved in the regulation of many different cellular processes, including cell growth, differentiation, and survival. SLC39A3 has been shown to interact with TrkB and enhance its activity. This interaction between SLC39A3 and TrkB suggests that SLC39A3 may be a useful drug target for the treatment of various diseases that are characterized by the over-expression or dysfunction of TrkB.

Another potential application of SLC39A3 as a drug target is its role in the regulation of ion channels. Ion channels are critical for the proper functioning of many different cellular processes, including muscle contractions and nerve signaling. SLC39A3 has been shown to be involved in the regulation of ion channels in various tissues, including the brain and heart. This suggests that SLC39A3 may be a useful target for the treatment of disorders that are characterized by the disruption of ion channels.

In addition to its potential as a drug target, SLC39A3 is also a potential biomarker for a variety of different diseases. Its ability to interact with a variety of different molecules makes it a useful tool for the detection and diagnosis of various diseases. For example, SLC39A3 has been shown to be involved in the regulation of the development and progression of cancer. This suggests that SLC39A3 may be a useful biomarker for the detection and treatment of cancer.

In conclusion, SLC39A3 is a protein that is expressed in various tissues throughout the body and is involved in various signaling pathways. Its ability to interact with a variety of different molecules makes it an attractive candidate for drug targeting and as a biomarker for various diseases. Further research is needed to fully understand the role of SLC39A3 in these processes and its potential as a drug and biomarker.

Protein Name: Solute Carrier Family 39 Member 3

Functions: Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus. Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen

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