SLC2A12: A Protein Involved in Brain Function and Disease (G154091)

Target Name: SLC2A12

NCBI ID: G154091

SLC2A12: A Protein Involved in Brain Function and Disease

SLC2A12 (SLC2A12 (GLUT12)) is a protein that is expressed in various tissues throughout the body. It is a member of the SLC2A family, which is known for its role in intracellular signaling. SLC2A12 is primarily expressed in the brain, where it is involved in the regulation of neural circuits and behaviors.

One of the unique aspects of SLC2A12 is its ability to interact with other proteins that are expressed in the brain, including the protein known as GLUT12. GLUT12 is a glucose transporter that is involved in the uptake and storage of glucose in the brain. SLC2A12 has been shown to interact with GLUT12 and to regulate the activity of GLUT12.

SLC2A12 is also involved in the regulation of ion channels in the brain, which are responsible for the flow of electrical signals through the neurons. SLC2A12 has been shown to regulate the activity of these channels, which is important for the proper functioning of the neural circuits in the brain.

In addition to its role in neural circuits, SLC2A12 is also involved in the regulation of inflammation. Inflammation is a natural response of the immune system, but chronic inflammation can contribute to a range of diseases, including neurodegenerative disorders. SLC2A12 has been shown to regulate the activity of immune cells in the brain, which is important for the control of inflammation.

SLC2A12 is also a potential drug target in the treatment of various neurological disorders. For example, SLC2A12 has been shown to be involved in the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. By targeting SLC2A12 with drugs, it may be possible to treat these disorders and improve the quality of life for those who are affected.

In conclusion, SLC2A12 is a protein that is expressed in various tissues throughout the body and is involved in a wide range of processes in the brain. Its ability to interact with other proteins in the brain, including GLUT12, makes it an attractive target for drug development in the treatment of neurological disorders. Further research is needed to fully understand the role of SLC2A12 in neural circuits and to identify potential drugs that can target it effectively.

Protein Name: Solute Carrier Family 2 Member 12

Functions: Insulin-independent facilitative glucose transporter

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