SLC26A1: A Potential Drug Target and Biomarker (G10861)

Target Name: SLC26A1

NCBI ID: G10861

SLC26A1: A Potential Drug Target and Biomarker

SLC26A1 (also known as EDM4) is a gene that encodes a protein known as solute carrier family 26 member 1. The solute carrier family 26 is a family of proteins that are involved in the transport of various molecules, including medications, across cell membranes. SLC26A1 is a member of this family and is expressed in many different tissues and organs throughout the body.

One of the key functions of SLC26A1 is its role in the transport of drugs across cell membranes. Many drugs work by interacting with specific proteins on the surface of cells, and SLC26A1 is involved in facilitating this process. For example, some antidepressants work by binding to specific SLC26A1 subunits on the surface of neurons and altering the levels of neurotransmitters inside the cell. Other drugs, such as diuretics, work by inhibiting the activity of SLC26A1 and causing the body to retain more water, which can lead to weight loss.

In addition to its role in drug transport, SLC26A1 is also involved in the regulation of various physiological processes in the body. For example, SLC26A1 is involved in the uptake and release of ions and nutrients into and out of cells, as well as in the regulation of pH levels. It is also involved in the production of various signaling molecules, such as neurotransmitters and hormones.

SLC26A1 has also been identified as a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, some studies have suggested that high levels of SLC26A1 may be associated with an increased risk of certain cancers, such as breast and ovarian cancer. Additionally, SLC26A1 has been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases.

Despite the potential implications for drug targeting and biomarker research, more research is needed to fully understand the role of SLC26A1 in the body. Many scientists are currently working to develop new treatments for diseases that involve SLC26A1, and there is a growing interest in the potential of targeting this protein with drugs or other therapeutic agents.

In conclusion, SLC26A1 is a gene that encodes a protein that is involved in a variety of physiological processes in the body. Its role in drug transport and regulation of various bodily functions makes it a potential target for new therapies. Further research is needed to fully understand the implications of SLC26A1 for human health and disease.

Protein Name: Solute Carrier Family 26 Member 1

Functions: Sodium-independent sulfate anion transporter (PubMed:12713736, PubMed:27125215). Can transport other anions including bicarbonate, thiosulfate and oxalate by mediating sulfate-thiosulfate, sulfate-hydrogencarbonate and sulfate-oxalate anion exchange (PubMed:12713736, PubMed:27125215). Mediates oxalate-hydrogencarbonate anion exchange (By similarity)

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