SLC22A5: Potential Drug Targets and Biomarkers (G6584)

Target Name: SLC22A5

NCBI ID: G6584

SLC22A5: Potential Drug Targets and Biomarkers

SLC22A5 (SLC22A5 variant 2) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a member of the SLC family of transmembrane proteins, which are known for their ability to transport various molecules across the cell membrane. One of the unique features of SLC22A5 is its potential as a drug target or biomarker.

SLC22A5 has been shown to play a role in a variety of physiological processes in the body. For example, it has been shown to be involved in the regulation of ion and water transport in the brain, which is important for cognitive function. SLC22A5 has also been shown to be involved in the regulation of insulin secretion from the pancreas, which is important for maintaining normal blood sugar levels.

In addition to its potential role in physiological processes, SLC22A5 has also been shown to be a potential drug target. Researchers have identified several potential drug targets for SLC22A5, including its role in the regulation of ion and water transport, insulin secretion, and cell survival.

One of the potential drug targets for SLC22A5 is its role in the regulation of ion and water transport. SLC22A5 has been shown to be involved in the regulation of the movement of ions and water molecules across the cell membrane. This is important for the proper functioning of many physiological processes in the body, including the regulation of pH and the transport of nutrients and waste products.

Another potential drug target for SLC22A5 is its role in insulin secretion. SLC22A5 has been shown to be involved in the regulation of insulin secretion from the pancreas, which is important for maintaining normal blood sugar levels. Insulin is a hormone that helps to regulate the levels of glucose in the body, and changes in insulin secretion can have a significant impact on blood sugar levels.

In addition to its potential role in the regulation of ion and water transport and insulin secretion, SLC22A5 has also been shown to be involved in cell survival. SLC22A5 has been shown to play a role in the regulation of cell survival and proliferation, which is important for the proper functioning of many tissues in the body.

Overall, SLC22A5 is a protein that has been shown to play a role in a variety of physiological processes in the body. Its potential as a drug target or biomarker makes it an attractive target for research in the field of drug development. Further studies are needed to fully understand the role of SLC22A5 in the regulation of ion and water transport, insulin secretion, and cell survival.

Protein Name: Solute Carrier Family 22 Member 5

Functions: Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine (PubMed:10454528, PubMed:10525100, PubMed:10966938, PubMed:17509700, PubMed:20722056). Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 11.3 (PubMed:10454528, PubMed:10525100, PubMed:10966938). In intestinal epithelia, transports the quorum-sensing pentapeptide CSF (competence and sporulation factor) from Bacillus Subtilis wich induces cytoprotective heat shock proteins contributing to intestinal homeostasis (PubMed:18005709). May also contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (Probable)

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