SLC15A3: A Protein Involved in Neurotransmitter and Ion Channel Regulation in Various Tissues

Target Name: SLC15A3

NCBI ID: G51296

SLC15A3: A Protein Involved in Neurotransmitter and Ion Channel Regulation in Various Tissues

SLC15A3, also known as Transient receptor potential cation channel subfamily 15 member 3, is a protein that is expressed in various tissues throughout the body. It is a member of the SLC family, which is known for its ability to transport small molecules across cell membranes . SLC15A3 is specifically a member of the 15th family of SLC proteins, known as the Transient receptor potential cation channel subfamily 15 (Transient receptor potential cation channel subfamily 15, TAC).

SLC15A3 is a 120-kDa protein that is expressed in the brain, heart, and skeletal muscles. It is primarily localized to the endoplasmic reticulum (ER), where it is involved in the transport of various molecules, including neurotransmitters and other signaling molecules. SLC15A3 is also involved in the regulation of ion channels, which are critical for the proper functioning of neurons and other cells.

One of the primary functions of SLC15A3 is to regulate the neurotransmitter uptake and release systems. It is known to play a role in the uptake of several neurotransmitters, including dopamine, serotonin, and nitric oxide. SLC15A3 is also involved in the release of these neurotransmitters , which is critical for the proper functioning of the brain and other nervous system cells.

In addition to its role in neurotransmitter regulation, SLC15A3 is also involved in the regulation of ion channels. It is a member of the Transient receptor potential cation channel subfamily 15, which is known for its ability to regulate the movement of positively charged ions through cell membranes. SLC15A3 is involved in the regulation of several different types of ion channels, including the calcium ion channels (Ca2+ channels) and the potassium ion channels (K+ channels).

SLC15A3 is also involved in the regulation of several intracellular signaling pathways. It is a member of the SLC family, which is known for its ability to transport small molecules across cell membranes. TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway.

SLC15A3 is also involved in the regulation of cellular signaling pathways that are critical for the development and maintenance of tissues. It is a member of the SLC family, which is known for its ability to transport small molecules across cell membranes. Regulation of several cellular signaling pathways, including the Wnt signaling pathway, the Hedgehog signaling pathway, and the Notch signaling pathway.

SLC15A3 is also involved in the regulation of the immune response. It is a member of the SLC family, which is known for its ability to transport small molecules across cell membranes. SLC15A3 is involved in the regulation of several immune response pathways, including the migration of immune cells and the production of antibodies.

In conclusion, SLC15A3 is a protein that is involved in a wide range of cellular processes that are critical for the proper functioning of the brain and other tissues. It is a member of the SLC family, which is known for its ability to transport small molecules across cell membranes. SLC15A3 is involved in the regulation of neurotransmitter uptake and release systems, ion channel regulation, cellular signaling pathways, and several other processes that are critical for the development and maintenance of tissues. As a drug target or biomarker, SLC15A3 may be a valuable tool for the study of several

Protein Name: Solute Carrier Family 15 Member 3

Functions: Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity). Also able to transport carnosine (PubMed:31073693). Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity)

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