SLC10A4: A Potential Drug Target and Biomarker (G201780)
SLC10A4: A Potential Drug Target and Biomarker
Solute carrier family 10 (SLC10) member 4, also known as SLC10A4, is a protein that is expressed in various tissues and cells throughout the body. Its function in the body is not well understood, but research has shown that it plays a role in the transport of a variety of molecules, including drugs, across cell membranes. As a result, SLC10A4 has been identified as a potential drug target and biomarker for a variety of diseases.
SLC10A4 is a member of the SLC10 family, which is known for its role in the transport of small molecules across cell membranes. The SLC10 family consists of six members, including SLC10A1, SLC10A2, SLC10A3, SLC10A4, SLC10A5, and SLC10A6. These proteins are characterized by the presence of a transmembrane segment (TMS) and a cytoplasmic tail (CT), as well as a variable region (VR) that is responsible for the specificity of the protein for its transport target.
SLC10A4 is a 124- amino acid protein that is expressed in various tissues and cells, including the brain, heart, liver, and pancreas. It is primarily localized to the endoplasmic reticulum (ER), which is the final destination for many proteins that are synthesized in the cytoplasm to be translated into functional proteins. The ER is a specialized organelle that is responsible for the quality control and sorting of proteins, and is known for its ability to transport proteins across the membrane and to regulate the levels of intracellular proteins.
SLC10A4 has been shown to play a role in the transport of a variety of molecules across cell membranes, including drugs that are used to treat a variety of diseases. For example, SLC10A4 has been shown to transport a variety of drugs, including statins, antidepressants, and antipsychotics, across cell membranes. This suggests that SLC10A4 may be a useful target for drugs that are used to treat these diseases.
In addition to its role in drug transport, SLC10A4 has also been shown to play a role in the regulation of cellular processes that are important for overall health. For example, SLC10A4 has been shown to be involved in the regulation of the levels of intracellular proteins, including those that are involved in cell signaling and metabolism. This suggests that SLC10A4 may be a useful target for drugs that are used to treat conditions that are characterized by the overproduction or underproduction of intracellular proteins.
SLC10A4 has also been shown to play a role in the regulation of cellular processes that are important for the development and progression of a variety of diseases. For example, SLC10A4 has been shown to be involved in the regulation of the migration of cancer cells, which is a critical step in the development of many types of cancer. This suggests that SLC10A4 may be a useful target for drugs that are used to inhibit the migration of cancer cells.
In conclusion, SLC10A4 is a protein that has been shown to play a role in the transport of various molecules across cell membranes, including drugs that are used to treat a variety of diseases. Its function in the body is not well understood, but research has shown that it plays an important role in the regulation of cellular processes that are important for overall health. As a result, SLC10A4 has been identified as a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand its role in the body and to develop effective treatments for
Protein Name: Solute Carrier Family 10 Member 4
Functions: Transporter for bile acids
More Common Targets
SLC10A5 | SLC10A6 | SLC10A7 | SLC11A1 | SLC11A2 | SLC12A1 | SLC12A2 | SLC12A2-DT | SLC12A3 | SLC12A4 | SLC12A5 | SLC12A5-AS1 | SLC12A6 | SLC12A7 | SLC12A8 | SLC12A9 | SLC13A1 | SLC13A2 | SLC13A3 | SLC13A4 | SLC13A5 | SLC14A1 | SLC14A2 | SLC15A1 | SLC15A2 | SLC15A3 | SLC15A4 | SLC15A5 | SLC16A1 | SLC16A10 | SLC16A11 | SLC16A12 | SLC16A13 | SLC16A14 | SLC16A2 | SLC16A3 | SLC16A4 | SLC16A5 | SLC16A6 | SLC16A6P1 | SLC16A7 | SLC16A8 | SLC16A9 | SLC17A1 | SLC17A2 | SLC17A3 | SLC17A4 | SLC17A5 | SLC17A6 | SLC17A7 | SLC17A8 | SLC17A9 | SLC18A1 | SLC18A2 | SLC18A3 | SLC18B1 | SLC19A1 | SLC19A2 | SLC19A3 | SLC1A1 | SLC1A2 | SLC1A3 | SLC1A4 | SLC1A5 | SLC1A6 | SLC1A7 | SLC20A1 | SLC20A1-DT | SLC20A2 | SLC22A1 | SLC22A10 | SLC22A11 | SLC22A12 | SLC22A13 | SLC22A14 | SLC22A15 | SLC22A16 | SLC22A17 | SLC22A18 | SLC22A18AS | SLC22A2 | SLC22A20P | SLC22A23 | SLC22A24 | SLC22A25 | SLC22A3 | SLC22A31 | SLC22A4 | SLC22A5 | SLC22A6 | SLC22A7 | SLC22A8 | SLC22A9 | SLC23A1 | SLC23A2 | SLC23A3 | SLC24A1 | SLC24A2 | SLC24A3 | SLC24A3-AS1