SKIC2: A Potential Drug Target and Biomarker for the Treatment of Inflammatory Diseases

Target Name: SKIC2

NCBI ID: G6499

SKIC2: A Potential Drug Target and Biomarker for the Treatment of Inflammatory Diseases

SKIC2, short for SKI2, is a protein that is expressed in various tissues throughout the body. It is a member of the interleukin-1 family, which includes proteins that play a crucial role in the immune response and inflammation. The SKIC2 protein has been shown to be involved in the regulation of inflammation and has potential as a drug target or biomarker for the treatment of inflammatory diseases.

SKIC2 has been shown to be involved in the regulation of cytokine signaling pathways, which are critical for the initiation and regulation of the immune response. It has been shown to play a role in the regulation of T cell development and function, and has been shown to be involved in the regulation of the production of pro-inflammatory cytokines.

SKIC2 has also been shown to be involved in the regulation of inflammation in the brain, which is a critical site of inflammation and is involved in the development and progression of many inflammatory diseases, including Alzheimer's disease and multiple sclerosis. It has been shown to play a role in the regulation of neuroinflammation and has been shown to be involved in the development of neurodegeneration.

SKIC2 has also been shown to be involved in the regulation of inflammation in the skin, which is a site of chronic inflammation and is involved in the development and progression of many inflammatory diseases, including psoriasis and acne. It has been shown to play a role in the regulation of skin inflammation and has been shown to be involved in the development of skin deformities.

In conclusion, SKIC2 is a protein that is involved in the regulation of inflammation and has potential as a drug target or biomarker for the treatment of inflammatory diseases. Further research is needed to fully understand the role of SKIC2 in inflammation and to develop effective treatments for inflammatory diseases based on this understanding.

Protein Name: SKI2 Subunit Of Superkiller Complex

Functions: Helicase; has ATPase activity (PubMed:7610041). Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) (PubMed:16024656)

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