SIGLEC5: A Protein Potential Drug Target and Biomarker (G8778)

Target Name: SIGLEC5

NCBI ID: G8778

SIGLEC5: A Protein Potential Drug Target and Biomarker

Sialic acid-binding immunoglobulin-like lectin 5 (SIGLEC5) is a protein that is expressed in many different tissues throughout the body. It is a type oflectin, which is a type of protein that is found on the surface of many different cell types. Ligands for SIGLEC5 include sialic acids, which are a type of carbohydrate found on the surface of many different cell types.

SIGLEC5 is involved in many different processes throughout the body. It is involved in the immune response, and it has been shown to play a role in the development and progression of many different diseases. For example, SIGLEC5 has been shown to be involved in the development of cancer, and it has also been shown to contribute to the development of autoimmune diseases such as rheumatoid arthritis and type 1 diabetes.

One of the potential uses for SIGLEC5 as a drug target or biomarker is its ability to interact with sialic acids. This has led to the development of compounds that can bind to SIGLEC5 and prevent it from interacting with sialic acids, which may be useful for treating diseases that are caused by the overproduction or dysfunction of sialic acids.

Another potential use for SIGLEC5 as a drug target is its role in the development of cancer. Many studies have shown that SIGLEC5 is involved in the development and progression of many different types of cancer, including breast, ovarian, and prostate cancer. Compounds that can inhibit the activity of SIGLEC5 have been shown to be effective in treating these types of cancer.

In addition to its potential as a drug target, SIGLEC5 has also been shown to be a potential biomarker for several different diseases. For example, SIGLEC5 has been shown to be involved in the development and progression of Alzheimer's disease, and it has also been shown to be involved in the development of other neurological conditions such as Parkinson's disease and multiple sclerosis.

Overall, SIGLEC5 is a protein that has the potential to be a drug target or biomarker for a variety of different diseases. Further research is needed to fully understand its role in these processes and to develop effective treatments.

Protein Name: Sialic Acid Binding Ig Like Lectin 5

Functions: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface

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