SHOC1: Key Regulator of Cell-Cell Adhesion and Potential Drug Target

Target Name: SHOC1

NCBI ID: G158401

SHOC1: Key Regulator of Cell-Cell Adhesion and Potential Drug Target

SHOC1 (short for SHO domain-containing 1) is a protein that is expressed in a variety of tissues and cells throughout the body. It is a key regulator of cell-cell adhesion, which is the process by which cells stick together to form tissues and organs.

SHOC1 has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its functions and interactions with other proteins have been extensively studied, and its potential as a drug target continue to attract research interest.

One of the key functions of SHOC1 is its role in cell-cell adhesion. SHOC1 is a member of the Shoc family of proteins, which are known for their ability to regulate cell-cell adhesion. This family of proteins includes other well-known proteins, such as SHOC2 and SHOC3, which are also involved in cell-cell adhesion.

SHOC1 functions by forming a complex with other proteins, including the transcription factor NF-kappa-B. This complex helps to regulate the expression of genes that are involved in cell-cell adhesion, as well as other processes that are important for cell growth and survival.

In addition to its role in cell-cell adhesion, SHOC1 is also involved in a number of other processes that are important for cell growth and development. For example, it is involved in the regulation of cell proliferation, and it has been shown to play a role in the development and progression of cancer.

SHOC1 has also been identified as a potential biomarker for a number of diseases. For example, SHOC1 has been shown to be overexpressed in a variety of cancer tissues, and it has been used as a biomarker for the diagnosis and prognosis of breast cancer.

In addition to its potential as a drug target and biomarker, SHOC1 is also of interest to researchers as a potential therapeutic target. For example, SHOC1 has been shown to be involved in a number of processes that are important for cell growth and survival, and drugs that can inhibit its activity may be effective in treating a variety of diseases.

Overall, SHOC1 is a protein that has important functions in cell growth and development, and it is of interest as a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand its mechanisms of action and its potential as a therapeutic target.

Protein Name: Shortage In Chiasmata 1

Functions: ATPase required during meiosis for the formation of crossover recombination intermediates (By similarity). Binds DNA: preferentially binds to single-stranded DNA and DNA branched structures (PubMed:29742103). Does not show nuclease activity in vitro, but shows ATPase activity, which is stimulated by the presence of single-stranded DNA (PubMed:29742103). Plays a key role in homologous recombination and crossing-over in meiotic prophase I in male and female germ cells (By similarity). Required for proper synaptonemal complex assembly and homologous chromosome pairing (By similarity). Requiref for recruitment TEX11 and MSH4 to recombination intermediates (By similarity)

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