Target Name: SHPRH
NCBI ID: G257218
Other Name(s): SHPRH_HUMAN | RAD5 | SNF2 histone linker PHD RING helicase | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | SHPRH variant 1 | bA545I5.2 | SNF2 histone linker PHD RING helicase, transcript variant 1 | SNF2, histone-linker, PHD and RING finger domain-containing helicase | E3 ubiquitin-protein ligase SHPRH | RING-type E3 ubiquitin transferase SHPRH | 2610103K11Rik | KIAA2023 | E3 ubiquitin-protein ligase SHPRH (isoform a)

SHPRH: A Protein Targeted for Drug and Biomarker Development

SHPRH (short for SHPRH_HUMAN) is a protein that is expressed in human tissues and has been shown to play a role in a variety of biological processes. Several studies have suggested that SHPRH may be a drug target or biomarker, and research is ongoing to determine its potential utility in these areas.

The SHPRH protein is a member of the tyrosine kinase family and is expressed in a variety of human tissues, including muscle, heart, and brain. It is involved in the regulation of cell proliferation and has been shown to play a role in the development and progression of several diseases, including cancer.

One of the key functions of SHPRH is its role in cell signaling. SHPRH has been shown to be involved in the regulation of cell proliferation and cell survival, and it has been shown to play a role in the development of cancer. For example, studies have shown that SHPRH can promote the growth and survival of cancer cells, and that inhibiting its activity can be an effective way to treat cancer.

Another function of SHPRH is its role in inflammation. SHPRH has been shown to be involved in the regulation of inflammation and has been shown to play a role in the development of several inflammatory diseases, including arthritis and asthma.

In addition to its role in cell signaling and inflammation, SHPRH has also been shown to be involved in the regulation of stem cell proliferation. SHPRH has been shown to play a role in the regulation of stem cell self-renewal and has been shown to play a role in the development of cancer.

Given its involvement in so many different functions, it is not surprising that SHPRH has been identified as a potential drug target or biomarker. Several studies have shown that SHPRH can be targeted by small molecules and that modifying its activity may be an effective way to treat a variety of diseases.

One of the most promising areas of research is the study of SHPRH as a drug target. Studies have shown that SHPRH can be targeted by small molecules, including inhibitors of tyrosine kinase activity, and that modifying its activity may be an effective way to treat a variety of diseases. For example, studies have shown that inhibiting SHPRH activity can be an effective way to treat cancer, and that modulating its activity may be an effective way to treat other diseases, such as arthritis and asthma.

In addition to its potential as a drug target, SHPRH has also been identified as a potential biomarker. Studies have shown that SHPRH is expressed in a variety of human tissues and that its levels can be used as a diagnostic marker for several diseases, including cancer. In addition, SHPRH has been shown to be involved in the regulation of cell signaling and inflammation, which makes it an attractive candidate for use as a biomarker for diseases associated with these processes.

Overall, SHPRH is a protein that has been shown to play a role in a variety of biological processes and has been identified as a potential drug target or biomarker. Further research is needed to fully understand its functions and to determine its potential utility in treating disease.

Protein Name: SNF2 Histone Linker PHD RING Helicase

Functions: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'

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SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1 | SKA3 | SKAP1 | SKAP1-AS2 | SKAP2 | Skeletal muscle troponin | SKI | SKIC2 | SKIC3 | SKIC8 | SKIDA1 | SKIL | SKINT1L | SKOR1 | SKOR2 | SKP1 | SKP1P2 | SKP2 | SLA