SHISA3: A Potential Drug Target and Biomarker (G152573)
SHISA3: A Potential Drug Target and Biomarker
Shisa homolog 3 (SHISA3) is a gene that encodes a protein known to be involved in various cellular processes. The protein produced by this gene has been shown to play a crucial role in the development and progression of various diseases, including cancer. As a result, SHISA3 has become a focus of interest for researchers as a potential drug target or biomarker.
The protein encoded by the SHISA3 gene is a key component of the immune response system. It is a member of the T-cell receptor (TCR) family, which is responsible for mediating the interactions between T cells and their respective antigens. The SHISA3 protein is known to be involved in the regulation of T-cell development, activation, and survival.
SHISA3 has been shown to be involved in the regulation of several cellular processes, including T-cell receptor signaling, apoptosis (programmed cell death), and inflammation. It has been shown to play a role in the development of cancer, including breast cancer, by promoting the growth and survival of cancer cells.
In addition to its role in cancer, SHISA3 has also been shown to be involved in the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. It has been shown to contribute to the pathogenesis of these diseases by promoting the production of immune-mediated damage in the affected tissues.
Given the involvement of SHISA3 in several cellular processes, it has potential as a drug target or biomarker for a variety of diseases. Targeting SHISA3 with small molecules or other therapeutic agents may offer new treatments for cancer, autoimmune diseases, and other conditions that involve the regulation of T-cell responses.
In conclusion, SHISA3 is a gene that has emerged as a promising target for drug development due to its involvement in the regulation of T-cell responses and the development of cancer. Further research is needed to fully understand the role of SHISA3 in these processes and to develop effective treatments for SHISA3-related diseases.
Protein Name: Shisa Family Member 3
Functions: Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling
More Common Targets
SHISA4 | SHISA5 | SHISA6 | SHISA7 | SHISA8 | SHISA9 | SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2 | SHOC1 | SHOC2 | Short transient receptor potential channel (TrpC) | SHOX | SHOX2 | SHPK | SHPRH | SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4