SHANK2: A Potential Drug Target and Biomarker (G22941)

Target Name: SHANK2

NCBI ID: G22941

SHANK2: A Potential Drug Target and Biomarker

SHANK2, or potassium hydrogen sulfate dimer, is a protein that is expressed in various tissues and cells of the body. It is a key regulator of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their stability.

Recent studies have identified SHANK2 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because SHANK2 plays a role in the development and maintenance of the cytoskeleton, and changes in the cytoskeleton can contribute to the development of these diseases.

One of the key functions of SHANK2 is its role in regulating the cytoskeleton in the development and maintenance of neurons. Neurons are responsible for transmitting electrical signals throughout the body, and their development and function are critical for many basic functions, including movement, sensation, and communication.

Shank2 plays a key role in regulating the cytoskeleton in neurons by controlling the amount of microtubules that exist in the cell. Microtubules are the structural elements that give cells their shape and help them maintain their stability, and they are involved in many important cellular processes, including the transport of molecules from one part of the cell to another and the regulation of cell growth.

Shank2 is also involved in the regulation of the cytoskeleton in the development and maintenance of other cells and tissues. For example, it has been shown to play a role in the regulation of muscle cell growth and function, and is involved in the development of the brain and nervous system.

In addition to its role in cell development and maintenance, SHANK2 is also a potential biomarker for a number of diseases. For example, SHANK2 has been shown to be overexpressed in a variety of cancer tissues, and may be a useful biomarker for the diagnosis and treatment of cancer.

Shank2 has also been shown to be involved in the regulation of pain perception and the modulation of pain sensitivity. This is an important area, as pain can be a sign of underlying biological dysfunction and can have a significant impact on a person's quality of life.

In conclusion, SHANK2 is a protein that plays a critical role in the development and maintenance of the cytoskeleton and is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of SHANK2 in these processes and to develop effective treatments.

Protein Name: SH3 And Multiple Ankyrin Repeat Domains 2

Functions: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction

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