Targeting SFMBT1 for Neurodegenerative Diseases (G51460)

Target Name: SFMBT1

NCBI ID: G51460

Targeting SFMBT1 for Neurodegenerative Diseases

SFMBT1, or small subunit fragment of the brain-derived neurotrophic factor (BDNF), is a protein that is expressed in various tissues throughout the body, including the nervous system, endothelial system, and epithelial system. It is a key regulator of neural stem cell proliferation and differentiation, and has been implicated in a wide range of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

SFMBT1 has also been identified as a potential drug target for the treatment of these conditions. By targeting the SFMBT1 protein, researchers hope to develop new treatments that can slow down or stop the progression of neurodegenerative diseases.

One way that researchers are targeting SFMBT1 is through the use of small molecules, which are drugs that can interact with the protein. These small molecules can either activate or inhibit the activity of SFMBT1, depending on their specific structure and concentration. Researchers have identified a number of potential small molecules that they believe may be effective in treat

Protein Name: Scm Like With Four Mbt Domains 1

Functions: Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis

More Common Targets