RNA-Nucleic Acid-Protein 24: Key Regulator of Cell Growth and Disease
RNA-Nucleic Acid-Protein 24: Key Regulator of Cell Growth and Disease
RNA-Nucleic Acid-Protein 24 (RNF24) is a protein that is expressed in various tissues of the human body. It is a key regulator of cell growth, differentiation, and inflammation. The RNA-Nucleic Acid-Protein (RNP) family is a transmembrane protein that consists of four subunits: RNP1, RNP2, RNP3, and RNP4. RNP2 is a key component of the RNP2-RNP complex, which plays a crucial role in regulating various cellular processes such as cell adhesion, migration, and transcriptional regulation.
RNP2 is a 24-kDa protein that consists of 191 amino acid residues. It has a characteristic transmembrane domain that is composed of a catalytic center, a transmembrane region, and a cytoplasmic tail. The transmembrane region of RNP2 contains a unique feature that is conserved in all RNP2 subunits, known as the N-terminal hypervariable region (HVR).
The N-terminal HVR is a region that is highly conserved across different species, and is involved in various cellular processes. It is a site of protein-protein interaction that is important for RNP2 stability and functions. The N-terminal HVR is also involved in the regulation of cellular processes such as cell adhesion, migration, and transcriptional regulation.
RNP2 has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. It is a potential drug target and biomarker due to its involvement in various cellular processes that are disrupted in these diseases.
One of the promising aspects of RNP2 is its potential as a drug target. RNP2 has been shown to play a role in various cellular processes that are important for cancer growth and progression. For example, RNP2 has been shown to promote the growth of various cancer cell types, including breast, ovarian, and colorectal cancer cells.
In addition to its role in cancer growth, RNP2 has also been implicated in the regulation of cellular processes that are important for neurodegenerative diseases. For example, RNP2 has been shown to play a role in the regulation of neurotransmitter synthesis and release, as well as the regulation of neuronal excitability.
RNP2 has also been implicated in the regulation of autoimmune diseases. For example, RNP2 has been shown to play a role in the regulation of T cell development and function, as well as the regulation of inflammation.
In conclusion, RNP2 is a protein that is expressed in various tissues of the human body and plays a crucial role in cell growth, differentiation, and inflammation. The N-terminal HVR is a key region that is involved in various cellular processes and is a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of RNP2 in these diseases and to develop effective therapies that target RNP2.
Protein Name: Ring Finger Protein 24
Functions: May play a role in TRPCs intracellular trafficking
More Common Targets
RNF25 | RNF26 | RNF31 | RNF32 | RNF32-DT | RNF34 | RNF38 | RNF39 | RNF4 | RNF40 | RNF41 | RNF43 | RNF44 | RNF5 | RNF5P1 | RNF6 | RNF7 | RNF7P1 | RNF8 | RNFT1 | RNFT2 | RNGTT | RNH1 | RNLS | RNMT | RNPC3 | RNPC3-DT | RNPEP | RNPEPL1 | RNPS1 | RNPS1P1 | RNR1 | RNR2 | RNU1-1 | RNU1-100P | RNU1-108P | RNU1-11P | RNU1-134P | RNU1-18P | RNU1-3 | RNU1-31P | RNU1-32P | RNU1-36P | RNU1-38P | RNU1-4 | RNU1-42P | RNU1-55P | RNU1-61P | RNU1-63P | RNU1-72P | RNU1-73P | RNU1-78P | RNU1-7P | RNU1-82P | RNU1-88P | RNU105B | RNU11 | RNU12 | RNU2-1 | RNU2-17P | RNU2-2P | RNU2-4P | RNU2-54P | RNU2-5P | RNU2-6P | RNU4-1 | RNU4-14P | RNU4-2 | RNU4-30P | RNU4-33P | RNU4-38P | RNU4-39P | RNU4-46P | RNU4-53P | RNU4-62P | RNU4-6P | RNU4-76P | RNU4-82P | RNU4-87P | RNU4-91P | RNU4-9P | RNU4ATAC | RNU4ATAC11P | RNU4ATAC18P | RNU5A-1 | RNU5A-4P | RNU5A-8P | RNU5B-1 | RNU5B-4P | RNU5D-1 | RNU5E-1 | RNU5E-6P | RNU5F-1 | RNU6-1 | RNU6-1003P | RNU6-1004P | RNU6-1052P | RNU6-1054P | RNU6-1067P | RNU6-1076P