TWF2: Potential Drug Target and Biomarker for Various Diseases
TWF2: Potential Drug Target and Biomarker for Various Diseases
TWF2 (Tumor-associated protein 2) is a protein that is expressed in various tissues of the body, including the blood vessels, tissues, and organs. It is a glycoprotein that consists of four polypeptide chains A, B, C, and D. TWF2 has been identified as a potential drug target and biomarker for various diseases, including cancer.
TWF2 has been shown to play a role in several cellular processes, including cell adhesion, migration, and invasion. It is a co-factor for the Focal Adhesion kinase (FAK), which is a protein that is involved in cell-cell adhesion and has been implicated in various diseases, including cancer. TWF2 has also been shown to interact with the transcription factor, NF-kappa-B, and the protein, PDGF-BB, which are involved in cell proliferation and survival.
TWF2 has also been shown to be involved in the regulation of the immune response. It is a co-factor for the protein, PD-L1, which is involved in the regulation of immune responses and has been implicated in various diseases, including cancer. TWF2 has also been shown to interact with the immune checkpoint protein, PD-1, which is involved in immune responses and has been implicated in various diseases, including cancer.
TWF2 has been shown to play a role in the regulation of cell survival and apoptosis. It is a co-factor for the protein, BCL-2, which is involved in the regulation of cell survival and apoptosis. TWF2 has also been shown to interact with the protein, p53, which is involved in the regulation of cell survival and apoptosis.
TWF2 has also been shown to play a role in the regulation of the blood-brain barrier. It is a co-factor for the protein, NG2, which is involved in the regulation of the blood-brain barrier and has been implicated in various diseases, including cancer. TWF2 has also been shown to interact with the protein, PDGFR-尾, which is involved in the regulation of the blood-brain barrier and has been implicated in various diseases, including cancer.
TWF2 has also been shown to play a role in the regulation of inflammation. It is a co-factor for the protein, TNF-伪, which is involved in inflammation and has been implicated in various diseases, including cancer. TWF2 has also been shown to interact with the protein, IL-6, which is involved in inflammation and has been implicated in various diseases, including cancer.
In conclusion, TWF2 is a protein that has been shown to play a role in several cellular processes, including cell adhesion, migration, and invasion, as well as the regulation of the immune response, cell survival and apoptosis, and the blood-brain barrier. It is a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the role of TWF2 in these processes and to develop effective treatments for these diseases.
Protein Name: Twinfilin Actin Binding Protein 2
Functions: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity)
More Common Targets
TWIST | TWIST1 | TWIST2 | TWNK | TWSG1 | TWSG1-DT | TXK | TXLNA | TXLNB | TXLNG | TXLNGY | TXN | TXN2 | TXNDC11 | TXNDC12 | TXNDC15 | TXNDC16 | TXNDC17 | TXNDC2 | TXNDC5 | TXNDC8 | TXNDC9 | TXNIP | TXNL1 | TXNL1P1 | TXNL4A | TXNL4B | TXNP6 | TXNRD1 | TXNRD2 | TXNRD3 | TXNRD3NB | TYK2 | TYMP | TYMS | TYMSOS | Type II Transmembrane serine protease | TYR | TYRO3 | TYRO3P | TYROBP | Tyrosine Kinase | Tyrosine-Protein Kinase ABL | Tyrosine-Protein Kinases Src | Tyrosyl-DNA phosphodiesterase TDP | TYRP1 | TYSND1 | TYW1 | TYW1B | TYW3 | U2 small nuclear ribonucleoprotein auxiliary factor | U2AF1 | U2AF1L4 | U2AF2 | U2SURP | U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex | U5 small nuclear ribonucleoprotein complex | U7 snRNP complex | UACA | UAP1 | UAP1L1 | UBA1 | UBA2 | UBA3 | UBA5 | UBA52 | UBA52P1 | UBA6 | UBA6-DT | UBA7 | UBAC1 | UBAC2 | UBAC2-AS1 | UBALD1 | UBALD2 | UBAP1 | UBAP1L | UBAP2 | UBAP2L | UBASH3A | UBASH3B | UBB | UBBP1 | UBBP2 | UBBP4 | UBC | UBD | UBDP1 | UBE2A | UBE2B | UBE2C | UBE2CP3 | UBE2CP4 | UBE2D1 | UBE2D2 | UBE2D3 | UBE2D3P1 | UBE2D4 | UBE2DNL | UBE2E1