Target Name: WFIKKN1
NCBI ID: G117166
Other Name(s): WFKN1_HUMAN | GASP2 | GASP-2 | WAP, FS, Ig, KU, and NTR-containing protein | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | Growth and differentiation factor-associated serum protein 2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | hGASP-2 | RJD2 | growth and differentiation factor-associated serum protein 2 | WAP four-disulfide core domain 20A | WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein | WFDC20A | WFIKKN | C16orf12 | WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing protein

WFIKKN1: A Potential Drug Target for Brain Health

WFIKKN1 (WFKN1_HUMAN), a gene product of the WFKN1 gene, is a protein that has been shown to play a significant role in various cellular processes in the human body. The WFKN1 gene is located on chromosome 6 and is responsible for the production of a protein that is involved in the development and maintenance of the blood-brain barrier.

The blood-brain barrier is a specialized barrier that separates the brain from the surrounding blood vessels and is responsible for maintaining the health and integrity of the brain. The blood-brain barrier is highly selective, meaning that it allows certain substances to enter the brain while rejecting others. This is important for maintaining the stability and integrity of the brain and for protecting it from harmful substances.

WFIKKN1 is a member of the Tetraspanin family, a group of proteins that are known for their role in maintaining the stability of various cell structures. The Tetraspanin family includes four proteins: WFIKKN1, WFIKKN2, WFIKKN3, and WFIKKN4. These proteins are involved in the regulation of various cellular processes, including cell signaling, cell adhesion, and cytoskeletal organization.

WFIKKN1 has been shown to play a role in the regulation of the blood-brain barrier. Studies have shown that WFIKKN1 is involved in the formation and maintenance of the blood-brain barrier, as well as its function in regulating the movement of cells into and out of the brain.

In addition to its role in the blood-brain barrier, WFIKKN1 has also been shown to be involved in the regulation of various cellular processes that are important for brain development and function. For example, studies have shown that WFIKKN1 is involved in the regulation of neuron migration, the formation of neural circuits, and the regulation of synaptic plasticity.

Given the involvement of WFIKKN1 in various cellular processes that are important for brain health and development, it is a potential drug target or biomarker. Researchers are currently working to develop new treatments for various neurological and psychiatric disorders by targeting WFIKKN1 and its associated proteins.

In conclusion, WFIKKN1 is a protein that has been shown to play a significant role in various cellular processes in the human body. Its role in the regulation of the blood-brain barrier and its involvement in the regulation of various cellular processes that are important for brain development and function make it a potential drug target or biomarker. Further research is needed to fully understand the role of WFIKKN1 in the regulation of brain health and to develop new treatments for various neurological and psychiatric disorders.

Protein Name: WAP, Follistatin/kazal, Immunoglobulin, Kunitz And Netrin Domain Containing 1

Functions: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity)

More Common Targets

WFIKKN2 | WFS1 | WHAMM | WHAMMP1 | WHAMMP2 | WHAMMP3 | WHRN | WIF1 | WIPF1 | WIPF2 | WIPF3 | WIPI1 | WIPI2 | WIZ | WLS | WNK1 | WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N | XPA | XPC