Target Name: SUN5
NCBI ID: G140732
Other Name(s): sad1 and UNC84 domain-containing protein 5 | Sad1 and UNC84 domain containing 5 | SUN domain-containing protein 5 | TSARG4 | SPAG4L | SUN5_HUMAN | SPGF16 | sperm-associated antigen 4-like protein | Sperm-associated antigen 4-like protein | Testis and spermatogenesis related gene 4 | DJ726C3.1 | testis and spermatogenesis-related gene 4 protein | Testis and spermatogenesis-related gene 4 protein | epididymis secretory sperm binding protein | Sad1 and UNC84 domain-containing protein 5 | dJ726C3.1 | testis and spermatogenesis related gene 4

Exploring the Potential Drug Target and Biomarker Sun5: A Sad1 and UNC84 Domain-Containing Protein

Introduction

Sun5, also known as sad1 and UNC84 domain-containing protein 5, is a protein that has been identified in various cellular processes. It plays a crucial role in the regulation of cell growth, differentiation, and survival. The sad1 gene, which encodes the protein Sun5, has been implicated in the development and progression of various diseases, including cancer. As a result, targeting Sun5 has been identified as a promising strategy for the development of new treatments. In this article, we will explore the potential drug target and biomarker that Sun5 may be.

Potential Drug Target: Sun5 as a cancer treatment target

Sun5 has been shown to play a significant role in the regulation of cell growth and apoptosis. It has been shown to promote the growth of cancer cells and to inhibit the death of cancer cells. This suggests that Sun5 may be an attractive drug target for cancer treatment.

One of the key advantages of targeting Sun5 is its expressed expression in various tissues and organs, including cancer cells. Additionally, Sun5 has been shown to be overexpressed in various types of cancer, which makes it an attractive target for small molecule inhibitors.

Sun5 has also been shown to interact with several other proteins, including T-cell receptor tyrosine kinase (TCR), which is a critical regulator of cell growth and differentiation. This suggests that targeting Sun5 may also be a way to target TCR, which is a potential drug target for cancer.

Biomarker potential

Sun5 has also been shown to be involved in several cellular processes that are important for cancer progression. One of the key functions of Sun5 is its role in the regulation of cell apoptosis. Apoptosis is a natural process that helps remove damaged or dysfunctional cells from the body. However, cancer cells often evade apoptosis, which allows them to continue to grow and multiply.

Sun5 has been shown to regulate the apoptosis-associated protein (AP-120) through the inhibition of its activity. This suggests that targeting Sun5 may be a way to target cancer cells that are resistant to apoptosis.

Another function of Sun5 is its role in the regulation of cell signaling pathways, including the TGF-β pathway. TGF-β is a critical signaling pathway that regulates cell growth, differentiation, and survival. Sun5 has been shown to be involved in the regulation of TGF-β signaling, which suggests that targeting Sun5 may be a way to target cells that are dependent on TGF-β signaling.

Conclusion

In conclusion, Sun5, also known as sad1 and UNC84 domain-containing protein 5, is a protein that has been identified in various cellular processes. Its expressed expression and regulation in various tissues and organs make it an attractive target for drug development. The potential drug target for Sun5 is its role in the regulation of cell growth and apoptosis, as well as its involvement in the TGF-β signaling pathway. Further research is needed to fully understand the role of Sun5 in cancer progression and to develop effective treatments.

Protein Name: Sad1 And UNC84 Domain Containing 5

Functions: Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope

More Common Targets

SUOX | Superoxide dismutase (SOD) | Suppressor of cytokine signaling (SOCS) | SUPT16H | SUPT20H | SUPT20HL1 | SUPT20HL2 | SUPT3H | SUPT4H1 | SUPT5H | SUPT6H | SUPT7L | SUPV3L1 | SURF complex | SURF1 | SURF2 | SURF4 | SURF6 | Survival of motor neuron (SMN) complex | SUSD1 | SUSD2 | SUSD3 | SUSD4 | SUSD5 | SUSD6 | SUV39H1 | SUV39H2 | SUZ12 | SUZ12P1 | SV2A | SV2B | SV2C | SVBP | SVEP1 | SVIL | SVIL-AS1 | SVIL2P | SVIP | SVOP | SVOPL | SWAP complex | SWAP70 | SWI5 | SWI5-SFR1 complex | SWINGN | SWSAP1 | SWT1 | SYAP1 | SYBU | SYCE1 | SYCE1L | SYCE2 | SYCE3 | SYCN | SYCP1 | SYCP2 | SYCP2L | SYCP3 | SYDE1 | SYDE2 | SYF2 | SYK | SYMPK | SYN1 | SYN2 | SYN3 | Synaptotagmin | SYNC | SYNCRIP | Syndecan | SYNDIG1 | SYNDIG1L | SYNE1 | SYNE1-AS1 | SYNE2 | SYNE3 | SYNE4 | SYNGAP1 | SYNGR1 | SYNGR2 | SYNGR3 | SYNGR4 | SYNJ1 | SYNJ2 | SYNJ2BP | SYNM | SYNM-AS1 | SYNPO | SYNPO2 | SYNPO2L | SYNPO2L-AS1 | SYNPR | SYNPR-AS1 | SYNRG | Syntaxin | Synuclein | SYP | SYPL1 | SYPL2 | SYS1