Syndecan: A Protein Involved in Various Diseases (P42003)

Target Name: Syndecan

NCBI ID: P42003

Other Name(s): SYND

Syndecan: A Protein Involved in Various Diseases

Syndecan (nonspecified subtype) (SYND) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the decan family of proteins, which are characterized by the presence of a conserved domain that is involved in the formation of a helical structure.

One of the unique features of Syndecan is its ability to form aggregates, which can be either in solution or in a cell culture environment. These aggregates are composed of repetitive units of the protein that are held together by disulfide bonds. This unique structure allows Syndecan to form a tight, organized structure that is involved in various cellular processes.

Syndecan has also been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its involvement in these diseases has led to its potential as a drug target or biomarker.

One of the main mechanisms by which Syndecan is involved in disease is its role in the development and progression of cancer. Syndecan has been shown to be involved in the regulation of cell proliferation, and it has been shown to promote the growth and survival of cancer cells.

In addition to its role in cancer, Syndecan is also involved in the development and progression of neurodegenerative diseases. These diseases are characterized by the progressive loss of brain cells and the development of progressive neurological symptoms. Syndecan has been shown to be involved in the regulation of neurotransmitter release and the maintenance of the integrity of neural tissues, and its involvement in these processes may make it a useful target for the development of neurodegenerative drugs.

Syndecan is also involved in the regulation of autoimmune disorders, in which the immune system attacks the body's own tissues. In these disorders, Syndecan has been shown to play a role in the regulation of T cell function and the regulation of inflammation.

In conclusion, Syndecan is a protein that is expressed in various tissues of the body and is involved in a variety of cellular processes. Its unique structure and its involvement in the development and progression of cancer, neurodegenerative diseases, and autoimmune disorders make it a potential drug target or biomarker. Further research is needed to fully understand the role of Syndecan in these processes and to develop effective treatments for these diseases.

Protein Name: Syndecan (nonspecified Subtype)

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