SYT12: A promising drug target and biomarker for the treatment of neurodegenerative diseases
SYT12: A promising drug target and biomarker for the treatment of neurodegenerative diseases
Synaptotagmin 12 (SYT12) is a protein that plays a crucial role in the structure and function of the nervous system. It is a member of the neurotrophic factor receptor tyrosine kinase (NGT) family, which is involved in the regulation of neural growth, survival, and differentiation. SYT12 is expressed in various tissues of the central nervous system (CNS) and is involved in the development, maintenance, and modulation of neural circuits.
SYT12 has been identified as a potential drug target and biomarker for the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells, which results in the degenerative symptoms associated with the diseases.
The neurotrophic factor receptor tyrosine kinase (NGT) family plays a crucial role in the regulation of neural growth, survival, and differentiation. The NG
Protein Name: Synaptotagmin 12
Functions: Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids (By similarity). Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity)
More Common Targets
SYT13 | SYT14 | SYT15 | SYT15B | SYT16 | SYT17 | SYT2 | SYT3 | SYT4 | SYT5 | SYT6 | SYT7 | SYT8 | SYT9 | SYTL1 | SYTL2 | SYTL3 | SYTL4 | SYTL5 | SYVN1 | SZRD1 | SZRD1P1 | SZT2 | T-Box transcription factor (TBX) | T-Type Calcium Channel | TAAR1 | TAAR2 | TAAR3P | TAAR5 | TAAR6 | TAAR8 | TAAR9 | TAB1 | TAB2 | TAB2-AS1 | TAB3 | TAC1 | TAC3 | TAC4 | TACC1 | TACC2 | TACC3 | Tachykinin Receptor | TACO1 | TACR1 | TACR2 | TACR3 | TACSTD2 | TADA1 | TADA2A | TADA2B | TADA3 | TAF1 | TAF10 | TAF11 | TAF11L2 | TAF11L3 | TAF12 | TAF12-DT | TAF13 | TAF15 | TAF1A | TAF1A-AS1 | TAF1B | TAF1C | TAF1D | TAF1L | TAF2 | TAF3 | TAF4 | TAF4B | TAF5 | TAF5L | TAF5LP1 | TAF6 | TAF6L | TAF7 | TAF7L | TAF8 | TAF9 | TAF9B | TAFA1 | TAFA2 | TAFA3 | TAFA4 | TAFA5 | TAFAZZIN | TAGAP | TAGAP-AS1 | TAGLN | TAGLN2 | TAGLN3 | TAK1 | TAL1 | TAL2 | TALDO1 | TAM Receptor tyrosine kinase | TAMALIN | TAMM41 | TANC1