TACR3: A Protein Involved in The Immune Response (G6870)
TACR3: A Protein Involved in The Immune Response
TACR3 (TAC3R) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and kidneys. It is a member of the T-cell antigen receptor (TCR) family, which is a type of protein that is expressed in the immune system to recognize and respond to foreign substances in the body.
The TACR3 protein is composed of four distinct domains: an N-terminus, a transmembrane segment, a cytoplasmic tail, and a C-terminus. The N-terminus of TACR3 is a 24 amino acid residue that contains a nucleotide sequence that is similar to that of the T-cell antigen receptor alpha chain (TCR伪). The transmembrane segment is a 50 amino acid residue that spans the entire cell membrane and is involved in the formation of the T-cell receptor complex. The cytoplasmic tail is a 20 amino acid residue that extends from the cytoplasm of the T-cell and is involved in the maintenance of the T-cell receptor complex. The C-terminus is a 24 amino acid residue that is located in the cytoplasm and is involved in the recognition of foreign substances by the T-cell receptor.
TACR3 is a critical protein that is involved in the immune response. It is expressed in a variety of tissues, including the brain, heart, lungs, and kidneys, and is involved in the development and maintenance of the immune system.
One of the functions of TACR3 is to recognize foreign substances in the body and initiate an immune response. When a foreign substance binds to TACR3, it triggers the activation of the immune system and the production of antibodies. These antibodies are designed to recognize and neutralize the foreign substance, and they are released into the bloodstream to protect the body against infection.
Another function of TACR3 is to regulate the activity of the immune system. TACR3 is involved in the regulation of the activation and proliferation of T-cells, as well as the regulation of the production of antibodies. It is also involved in the regulation of the release of T-cells from the body, which is important for maintaining immune tolerance and avoiding the production of autoimmune diseases.
TACR3 is also involved in the regulation of cellular signaling processes. It is involved in the regulation of the signaling processes that occur between T-cells and other immune cells, as well as the regulation of the signaling processes that occur between T-cells and the brain. This involvement in cellular signaling processes is important for the regulation of the immune response and the maintenance of immune tolerance.
In conclusion, TACR3 is a critical protein that is involved in the immune response and cellular signaling processes. It is expressed in various tissues of the body and is involved in the development and maintenance of the immune system. Further research is needed to better understand the role of TACR3 in the immune response and to develop effective treatments for T-cell disorders.
Protein Name: Tachykinin Receptor 3
Functions: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P
More Common Targets
TACSTD2 | TADA1 | TADA2A | TADA2B | TADA3 | TAF1 | TAF10 | TAF11 | TAF11L2 | TAF11L3 | TAF12 | TAF12-DT | TAF13 | TAF15 | TAF1A | TAF1A-AS1 | TAF1B | TAF1C | TAF1D | TAF1L | TAF2 | TAF3 | TAF4 | TAF4B | TAF5 | TAF5L | TAF5LP1 | TAF6 | TAF6L | TAF7 | TAF7L | TAF8 | TAF9 | TAF9B | TAFA1 | TAFA2 | TAFA3 | TAFA4 | TAFA5 | TAFAZZIN | TAGAP | TAGAP-AS1 | TAGLN | TAGLN2 | TAGLN3 | TAK1 | TAL1 | TAL2 | TALDO1 | TAM Receptor tyrosine kinase | TAMALIN | TAMM41 | TANC1 | TANC2 | TANGO2 | TANGO6 | TANK | Tankyrase | TAOK1 | TAOK2 | TAOK3 | TAP1 | TAP2 | TAPBP | TAPBPL | TAPT1 | TAPT1-AS1 | TARBP1 | TARBP2 | TARDBP | TARDBPP1 | TARDBPP3 | TARID | TARM1 | TARP | TARS1 | TARS2 | TARS3 | TAS1R1 | TAS1R2 | TAS1R3 | TAS2R1 | TAS2R10 | TAS2R13 | TAS2R14 | TAS2R16 | TAS2R19 | TAS2R20 | TAS2R3 | TAS2R30 | TAS2R31 | TAS2R38 | TAS2R39 | TAS2R4 | TAS2R40 | TAS2R41 | TAS2R42 | TAS2R43 | TAS2R45 | TAS2R46