Heat Shock Factor 2: Stress Response and Gene Expression (G159119)

Target Name: HSFY2

NCBI ID: G159119

Heat Shock Factor 2: Stress Response and Gene Expression

Heat shock transcription factor (HSFY2), also known as heat shock factor (HSF) or Y-linked heat shock factor (YHSF), is a protein that plays a crucial role in the regulation of gene expression in response to heat stress. It is a key transcription factor that is activated in response to increased temperatures, which triggers the expression of genes involved in stress response, such as those involved in DNA damage repair, cell growth, and apoptosis.

HSFY2 is a member of the heat shock transcription factor (HSF) family, which includes a number of proteins that are involved in the regulation of gene expression in response to environmental stressors, including heat, cold, and radiation. These proteins are characterized by the presence of a nucleotide-binding oligomerization domain (NMOD), which is responsible for the binding of DNA sequences to the protein.

HSFY2 is a key transcription factor that is involved in the regulation of gene expression in response to heat stress. It is activated in response to increased temperatures, which triggers the expression of genes involved in stress response.

One of the key functions of HSFY2 is its ability to induce the expression of genes involved in DNA damage repair. This is important for ensuring that cells are able to repair DNA damage that can be caused by environmental stressors, such as radiation or thermal stress.

HSFY2 is also involved in the regulation of cell growth and apoptosis. It is able to induce the growth of cells under stress, and it can also induce cell death in response to certain stressors. This is important for ensuring that cells are able to respond to stress in a controlled and coordinated manner.

HSFY2 is also involved in the regulation of gene expression in response to other types of stressors, such as cold and radiation. It is able to induce the expression of genes involved in stress response in these conditions, which is important for ensuring that cells are able to adapt to and recover from these types of stressors.

In addition to its role in stress response, HSFY2 is also involved in the regulation of gene expression in response to other types of stimuli, such as growth factors and chemical inhibitors. This is important for ensuring that cells are able to respond to a wide range of different stimuli and maintain optimal cell function.

Overall, HSFY2 is a protein that plays a crucial role in the regulation of gene expression in response to heat stress. Its ability to induce the expression of genes involved in stress response and its involvement in the regulation of cell growth, apoptosis, and other types of stress response make it an attractive drug target and a potential biomarker for a variety of diseases.

Protein Name: Heat Shock Transcription Factor Y-linked 2

More Common Targets