Target Name: GRAMD4
NCBI ID: G23151
Other Name(s): MGC90497 | dA59H18.1 | GRAM domain-containing protein 4 | Death-inducing protein | death-inducing-protein | GRAM domain containing 4 | OTTHUMP00000197288 | GRAM domain-containing protein 4 (isoform 1) | GRAM domain containing 4, transcript variant 1 | MGC149847 | GRAM4_HUMAN | DIP | GRAMD4 variant 1 | KIAA0767 | dJ439F8.1

Grammd4: Potential Drug Targets and Diseases

Grammd4 (MGC90497) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key player in the regulation of cell growth and differentiation, and has been implicated in a number of diseases, including cancer. In this article, we will discuss the biology and potential drug targets of Grammmd4, as well as its potential as a biomarker for certain diseases.

Grammd4 and Cellular Biology
Grammd4 is a member of the transforming growth factor receptor (TGFR) family, which is a group of proteins that regulate cell growth and differentiation. TGFRs are composed of a transmembrane domain and a cytoplasmic tail, and are involved in the regulation of cell proliferation, differentiation, and survival.

Grammd4 is involved in the regulation of cell proliferation and differentiation by interacting with several different signaling pathways. For example, it has been shown to play a role in the regulation of mitochondrial function, and has been shown to interact with the protein p53, which is a well-known tumor suppressor protein.

In addition to its role in cell proliferation and differentiation, Grammmd4 is also involved in the regulation of cell survival. Studies have shown that Grammmd4 can interact with the protein Bcl-2, which is a protein that is known to play a role in the regulation of cell survival and has been implicated in a number of diseases, including cancer. The interaction between Grammmd4 and Bcl-2 has been shown to promote the survival of cancer cells, suggesting that it may be a potential drug target for cancer treatment.

Potential Drug Targets
Grammd4 is a protein that has potential as a drug target for a number of diseases. One of the main targets for Grammmd4 is the protein PDGFR, which is a receptor for the tyrosine kinase PDGF. PDGF is a potent signaling molecule that is involved in the regulation of cell growth and differentiation, and has been implicated in a number of diseases, including cancer.

Grammd4 has been shown to interact with PDGF, and studies have shown that the interaction between Grammmd4 and PDGF can promote the growth and survival of cancer cells. This suggests that Grammmd4 may be a potential drug target for cancer treatment.

Another potential drug target for Grammmd4 is the protein NF-kappa-B, which is a signaling molecule that is involved in the regulation of inflammation and immune responses. NF-kappa-B has been shown to interact with Grammmd4, and studies have shown that the interaction between Grammmd4 and NF-kappa-B can promote the development of cancer. This suggests that Grammmd4 may be a potential drug target for diseases that are characterized by inflammation or immune dysregulation.

Gmmnd4 and Disease
Grammd4 is involved in the regulation of a number of diseases, including cancer. Studies have shown that Grammmd4 is involved in the regulation of cell proliferation and differentiation, and that it is expressed in a number of tissues that are susceptible to cancer.

For example, studies have shown that Grammmd4 is involved in the regulation of cell proliferation and differentiation in the brain, and that it is expressed in the brain tissue of mice that have been treated with radiation. This suggests that Grammmd4 may be a potential drug target for diseases that affect the brain, such as cancer.

In addition to its role in cancer, Grammmd4 is also involved in the regulation of cell survival in diseases that affect the kidneys, such as chronic kidney disease. Studies have shown that Grammmd4 is involved in the regulation of

Protein Name: GRAM Domain Containing 4

Functions: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (PubMed:15565177). Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity)

More Common Targets

GRAMD4P2 | GRAMD4P5 | GRAMD4P7 | Granzyme | GRAP | GRAP2 | GRAPL | GRAPL-AS1 | GRASLND | GRB10 | GRB14 | GRB2 | GRB7 | GREB1 | GREB1L | GREM1 | GREM1-AS1 | GREM2 | GREP1 | GRHL1 | GRHL2 | GRHL3 | GRHL3-AS1 | GRHPR | GRIA1 | GRIA2 | GRIA3 | GRIA4 | GRID1 | GRID2 | GRID2IP | GRIFIN | GRIK1 | GRIK1-AS1 | GRIK1-AS2 | GRIK2 | GRIK3 | GRIK4 | GRIK5 | GRIN1 | GRIN2A | GRIN2B | GRIN2C | GRIN2D | GRIN3A | GRIN3B | GRINA | GRIP1 | GRIP2 | GRIPAP1 | GRK1 | GRK2 | GRK3 | GRK4 | GRK5 | GRK6 | GRK7 | GRM1 | GRM2 | GRM3 | GRM4 | GRM5 | GRM5-AS1 | GRM5P1 | GRM6 | GRM7 | GRM7-AS3 | GRM8 | GRM8-AS1 | GRN | Growth Factor Receptor-Bound Protein | GRP | GRPEL1 | GRPEL2 | GRPEL2-AS1 | GRPR | GRSF1 | GRTP1 | GRTP1-AS1 | GRWD1 | GRXCR1 | GRXCR2 | GS1-24F4.2 | GS1-600G8.3 | GSAP | GSC | GSC2 | GSDMA | GSDMB | GSDMC | GSDMD | GSDME | GSE1 | GSEC | GSG1 | GSG1L | GSG1L2 | GSK3A | GSK3B | GSKIP