Glycated Serum Albumin as A Drug Target for Diabetes (G145258)

Target Name: GSC

NCBI ID: G145258

Glycated Serum Albumin as A Drug Target for Diabetes

Glycated serum albumin (GSC), also known as glycosylated serum albumin, is a protein that is highly glycated in people with diabetes. GSC levels are higher in diabetic patients, and the higher the level, the higher the risk of developing diabetes.

GSC is a glycoprotein composed of two glycosylated serum albumin subunits: 伪-glucosidase and 尾-glucosidase. These subunits combine with sugar molecules through glycosylation reactions to form a glycoprotein complex. The higher the degree of glycosylation of GSC, the more tightly the sugar molecules are bound, forming a more stable glycoprotein complex.

GSC is elevated in diabetic patients, and its content is directly proportional to blood glucose levels in diabetic patients. Studies have shown that GSC is an independent predictor of diabetes, and the higher its content, the higher the patient's risk of developing diabetes.

GSC has attracted widespread attention as a drug target. Researchers are exploring the potential of GSCs as diabetes treatments. For example, some researchers are studying GSC as a target for treating diabetes by inhibiting GSC activity to lower blood sugar levels.

In addition, GSCs are also used as biomarkers for diabetes. Studies have shown that GSCs can serve as sensitive and predictive biomarkers in patients with diabetes. For example, GSC content can be used as an independent predictor of diabetes. The higher the GSC content, the higher the risk of developing diabetes.

As a new drug target, GSC has attracted widespread attention. Researchers are exploring the potential of GSCs as diabetes treatments and biomarkers. As research progresses, GSCs may provide new treatments and diagnostics for patients with diabetes.

Protein Name: Goosecoid Homeobox

Functions: Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals

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