GSTA2: Key Regulator of Cell Signaling and Disease (G2939)

Target Name: GSTA2

NCBI ID: G2939

GSTA2: Key Regulator of Cell Signaling and Disease

GSTA2 (GST-伪2) is a protein that is expressed in various tissues and cells in the human body. It is a key subunit of the G-protein-coupled receptor (GPCR) family 2 (GPCR2) which is a large family of transmembrane proteins that play a crucial role in cellular signaling. GSTA2 is a 21-kDa protein that is expressed in the brain, heart, skeletal muscles, and various other tissues in the body.

GSTA2 is involved in a wide range of physiological processes in the body, including cell signaling, neurotransmitter signaling, and inflammation. It is a key regulator of several signaling pathways that are involved in the regulation of pain, inflammation, and other physiological processes. GSTA2 has also been shown to be involved in the regulation of sleep-wake cycles, muscle tone, and other physiological processes that are important for maintaining proper body function.

GSTA2 has also been shown to be a potential drug target in several diseases. For example, GSTA2 has been shown to be involved in the regulation of pain perception and neuropathic pain, which is a type of pain that is caused by damage to the nervous system. GSTA2 has also been shown to be involved in the regulation of neuroinflammation, which is the inflammation that occurs in the brain and other nervous system tissues as a result of injury or disease.

In addition to its potential as a drug target, GSTA2 is also a potential biomarker for several diseases. For example, GSTA2 has been shown to be elevated in the blood of individuals with certain types of cancer, which suggests that it may be a useful biomarker for cancer diagnosis and treatment. Additionally, GSTA2 has been shown to be elevated in the urine of individuals with urinary tract infection (UTI), which suggests that it may be a useful biomarker for UTI diagnosis and treatment.

GSTA2 is also a potential therapeutic target for several other diseases. For example, GSTA2 has been shown to be involved in the regulation of blood pressure, which is an important factor in the development of cardiovascular disease. GSTA2 has also been shown to be involved in the regulation of insulin sensitivity, which is important for the development of type 2 diabetes. Additionally, GSTA2 has been shown to be involved in the regulation of muscle strength and function, which is important for maintaining physical activity and independence in older adults.

In conclusion, GSTA2 is a protein that is involved in a wide range of physiological processes in the body. It is a key regulator of several signaling pathways that are involved in the regulation of pain, inflammation, and other physiological processes. GSTA2 has also been shown to be involved in the regulation of sleep-wake cycles, muscle tone, and other physiological processes that are important for maintaining proper body function. Additionally, GSTA2 has been shown to be a potential drug target and biomarker for several diseases, including cancer, UTI, and cardiovascular disease. Further research is needed to fully understand the role of GSTA2 in the regulation of physiological processes and its potential as a therapeutic target.

Protein Name: Glutathione S-transferase Alpha 2

Functions: Catalyzes the conjugation of glutathione to a large variety of electrophilic compounds

More Common Targets