GTF2IRD1: A Potential Drug Target Or Biomarker (G9569)

Target Name: GTF2IRD1

NCBI ID: G9569

GTF2IRD1: A Potential Drug Target Or Biomarker

GTF2IRD1, also known as GTF2I repeat domain containing 1, is a non-coding RNA molecule that has been identified as a potential drug target or biomarker. GTF2IRD1 is a member of the GTF2I family, which is characterized by the presence of a specific repeat domain that is conserved across various species.

The GTF2IRD1 repeat domain is a small non-coding RNA molecule that is approximately 190 amino acids long. It is composed of a single exon that is located upstream of the start codon. The repeat domain is conserved across various species, including humans, and is involved in the formation of a stem-loop structure.

One of the unique features of GTF2IRD1 is its expression pattern. GTF2IRD1 is primarily expressed in the brain, specifically in the cerebral cortical cortical cortical regions. It is also expressed in other tissues, including the heart, liver, and pancreas. The expression pattern of GTF2IRD1 is highly consistent with the function of the gene, as it is involved in the development and maintenance of neural stem cells.

In addition to its expression pattern, GTF2IRD1 has also been shown to play a role in several cellular processes. For example, it has been shown to be involved in the regulation of stem cell proliferation and differentiation. GTF2IRD1 has also been shown to play a role in the regulation of the immune response, specifically in the regulation of T cell development.

As a potential drug target, GTF2IRD1 is of interest due to its involvement in several cellular processes that are important for human health. For example, GTF2IRD1 has been shown to be involved in the regulation of neural stem cell proliferation, which is important for the development and maintenance of neural tissue. GTF2IRD1 may also be involved in the regulation of the immune response, which is important for maintaining overall human health.

In conclusion, GTF2IRD1 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker. Its conservation in different species and its expression pattern in various tissues make it a promising candidate for further study. Further research is needed to fully understand the role of GTF2IRD1 in cellular processes and its potential as a drug target.

Protein Name: GTF2I Repeat Domain Containing 1

Functions: May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity)

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