GUCY2F: A Potential Drug Target and Biomarker (G2986)
GUCY2F: A Potential Drug Target and Biomarker
Gucy2f is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Gucy2 family, which includes several related proteins that are involved in various cellular processes. One of the most interesting features of Gucy2f is its potential as a drug target and biomarker.
The discovery of Gucy2f as a potential drug target comes from a study by the research group led by Dr. Qin Liu at the University of California, San Diego. The study identified Gucy2f as a protein that is expressed in the brain and is involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time. The researchers found that Gucy2f was highly expressed in the brains of mice and that overexpression of the gene led to increased synaptic plasticity.
Furthermore, Gucy2f was shown to play a role in the regulation of neural stem cell proliferation and differentiation. This suggests that Gucy2f may be a promising target for drugs that are aimed at enhancing or treating neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease.
As a potential biomarker, Gucy2f has been shown to be involved in the regulation of various cellular processes, including cell division, migration, and survival. This suggests that Gucy2f may be a useful marker for tracking the effectiveness of drugs in these diseases. In addition, Gucy2f has been shown to be involved in the regulation of inflammation, which is a major contributor to various diseases, including neurodegenerative diseases.
Gucy2f is also a potential target for cancer therapy. The Gucy2 family has been shown to be involved in the regulation of cell growth and survival, which may make Gucy2f a useful target for cancer treatments. Several studies have shown that Gucy2f is highly expressed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that Gucy2f may be a promising target for cancer therapies that are aimed at targeting these cancers.
In conclusion, Gucy2f is a protein that has been shown to be involved in various cellular processes that are important for the health and function of the body. The potential drug target and biomarker properties of Gucy2f make it an attractive target for further research and development. Further studies are needed to fully understand the role of Gucy2f in various cellular processes and its potential as a drug target and biomarker.
Protein Name: Guanylate Cyclase 2F, Retinal
Functions: Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (PubMed:7777544). Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity)
More Common Targets
GUCY2GP | GUF1 | GUK1 | GULOP | GULP1 | GUSB | GUSBP1 | GUSBP11 | GUSBP12 | GUSBP14 | GUSBP15 | GUSBP17 | GUSBP2 | GUSBP3 | GUSBP4 | GUSBP5 | GUSBP8 | GVINP1 | GVQW3 | GXYLT1 | GXYLT1P3 | GXYLT1P4 | GXYLT1P6 | GXYLT2 | GYG1 | GYG2 | GYPA | GYPB | GYPC | GYPE | GYS1 | GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9
