Target Name: H2BC12
NCBI ID: G85236
Other Name(s): H2BC12 variant 2 | H2BFAiii | H2B1K_HUMAN | histone 1, H2bk | H2B K | histone family member | H2B clustered histone 12 | Histone 1, H2bk | HIRIP1 | OTTHUMP00000016177 | H2BK | histone cluster 1, H2bk | Histone family member | HIST1H2BK | H2B/S | MGC131989 | histone cluster 1 H2B family member k | H2B clustered histone 12, transcript variant 2 | HIRA-interacting protein 1 | H2B histone family, member T | H2BFT | Histone H2B type 1-K

H2BC12: Potential Drug Target Or Biomarker

H2BC12 is a protein that is expressed in various tissues throughout the body, including the liver, pancreas, and blood vessels. It is a member of the H2B family, which is known for its role in the regulation of cell signaling processes. H2BC12 has been shown to play a role in the regulation of inflammation and fibrosis, and is potential drug target or biomarker.

The H2B family of proteins is known for its ability to regulate a wide range of cellular processes, including cell signaling, cell adhesion, and the regulation of inflammation. H2BC12 is a member of this family and is expressed in various tissues throughout the body.

One of the functions of H2BC12 is its role in the regulation of inflammation. H2BC12 has been shown to play a negative role in the regulation of inflammation and fibrosis. This is because H2BC12 is involved in the production of pro-inflammatory cytokines, which are responsible for driving the inflammatory response.

In addition to its role in inflammation, H2BC12 has also been shown to play a role in the regulation of fibrosis. Fibrosis is a process in which cells become abnormally organized and can cause a wide range of diseases, including heart disease, diabetes, and cancer. H2BC12 has been shown to be involved in the regulation of fibrosis by promoting the production of extracellular matrix (ECM) components.

H2BC12 has also been shown to play a role in the regulation of cell signaling processes. This is because H2BC12 is involved in the regulation of the activity of several intracellular signaling pathways, including the TGF-β pathway. The TGF-β pathway is a key regulator of cell signaling and is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and inflammation.

In conclusion, H2BC12 is a protein that is involved in a wide range of cellular processes and has been shown to play a negative role in the regulation of inflammation and fibrosis. As a potential drug target or biomarker, H2BC12 is a promising target for the development of new therapies for a wide range of diseases. Further research is needed to fully understand the role of H2BC12 in cellular processes and its potential as a drug target or biomarker.

Protein Name: H2B Clustered Histone 12

Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

More Common Targets

H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1 | H4C11 | H4C12 | H4C13 | H4C14 | H4C15 | H4C16 | H4C2 | H4C3 | H4C4 | H4C5 | H4C6 | H4C7 | H4C8 | H4C9 | H6PD | HAAO | HABP2 | HABP4 | HACD1 | HACD2 | HACD3 | HACD4 | HACE1 | HACL1 | HADH | HADHA | HADHAP1 | HADHB | HAFML | HAGH | HAGHL | HAGLR | HAGLROS | HAL | HAMP | HAND1 | HAND2 | HAND2-AS1 | HAO1 | HAO2 | HAO2-IT1 | HAP1 | HAPLN1 | HAPLN2 | HAPLN3 | HAPLN4 | HAPSTR1 | HAR1A | HAR1B | HARBI1 | HARS1 | HARS2