Target Name: H3C2
NCBI ID: G8358
Other Name(s): HIST1H3G | histone cluster 1, H3b | HIST1H3C | histone cluster 1 H3 family member b | Histone H3/c | H3/l | HIST1H3E | HIST1H3J | HIST1H3I | Histone H3/a | Histone H3/f | Histone H3/i | Histone H3.1 | H3 histone family, member L | histone 1, H3b | HIST1H3B | H3C12 | H3C6 | histone H3/l | HIST1H3A | H3 histone family, member K | H31_HUMAN | H3C7 | H3C3 | HIST1H3F | H3FL | HIST1H3H | Histone H3/k | H3C1 | H3C8 | Histone H3/d | Histone 1, H3a | H3C11 | histone 1, H3h | H3C4 | HIST1H3D | H3 clustered histone 2 | Histone H3/h | histone cluster 1, H3h | Histone H3/j | Histone H3/b | Histone cluster 1, H3b | H3C10 | histone cluster 1 H3 family member h | Histone H3/l | H3 histone family, member A

H3C2: A Potential Drug Target for Neural System Disorders

H3C2, also known as HIST1H3G, is a protein that is expressed in various tissues of the body, including the nervous system, and is involved in the development and maintenance of neural stem cells. The H3G gene is a member of the H3 gene family, which is known for its role in the development and maintenance of neural stem cells.

H3C2 has been shown to play a role in the regulation of neural stem cell proliferation and differentiation. It has been shown to be involved in the development of neural stem cells from postnatal neural tissue, and has been shown to play a role in the regulation of neural stem cell survival and proliferation.

H3C2 has also been shown to be involved in the development and maintenance of the nervous system. It has been shown to be involved in the development of the cerebral cortical development, and has been shown to play a role in the regulation of neuronal communication in the brain.

In addition to its role in the development and maintenance of neural stem cells and the nervous system, H3C2 has also been shown to have potential as a drug target. H3C2 has been shown to interact with various drug targets, including the transcription factor PDGF-BB, the DNA damage-response protein HDR1, and the cell-cycle regulator p21.

These interactions suggest that H3C2 may be a useful target for the development of new drugs for a variety of neural system disorders, including neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Overall, H3C2 is a protein that has the potential to be a drug target for a variety of neural system disorders. Further research is needed to fully understand its role and to develop new treatments.

Protein Name: H3 Clustered Histone 2

Functions: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

More Common Targets

H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1 | H4C11 | H4C12 | H4C13 | H4C14 | H4C15 | H4C16 | H4C2 | H4C3 | H4C4 | H4C5 | H4C6 | H4C7 | H4C8 | H4C9 | H6PD | HAAO | HABP2 | HABP4 | HACD1 | HACD2 | HACD3 | HACD4 | HACE1 | HACL1 | HADH | HADHA | HADHAP1 | HADHB | HAFML | HAGH | HAGHL | HAGLR | HAGLROS | HAL | HAMP | HAND1 | HAND2 | HAND2-AS1 | HAO1 | HAO2 | HAO2-IT1 | HAP1 | HAPLN1 | HAPLN2 | HAPLN3 | HAPLN4 | HAPSTR1 | HAR1A | HAR1B | HARBI1 | HARS1 | HARS2 | HAS1 | HAS2 | HAS2-AS1 | HAS3 | HASPIN | HAT1 | HAUS1 | HAUS1P1 | HAUS2 | HAUS3 | HAUS4 | HAUS5 | HAUS6 | HAUS7 | HAUS8 | HAVCR1 | HAVCR1P1 | HAVCR2 | HAX1 | HAX1P1 | HBA1 | HBA2 | HBAP1 | HBB | HBBP1 | HBD | HBE1 | HBEGF | HBG1 | HBG2 | HBM | HBO1 complex | HBP1 | HBQ1 | HBS1L | HBZ