HAS1: A Drug Target / Disease Biomarker (G3036)

Target Name: HAS1

NCBI ID: G3036

HAS1: A Drug Target / Disease Biomarker

HAS1, also known as heat-associated protein 1, is a protein that is expressed in a variety of tissues and cells in the body. It is characterized by the presence of a distinct N-terminal translocation domain, which is a region of the protein that is able to bind to certain types of heat-associated proteins (HAPs) and is involved in the regulation of cellular processes such as DNA double-strand repair and protein folding.

One of the unique features of HAS1 is its ability to form a complex with the protein p16INK4a, which is a well-known regulator of the Ink4a gene. This complex plays a role in the regulation of cellular processes such as cell growth, apoptosis, and DNA repair, and is thought to be involved in the development and progression of a variety of diseases, including cancer.

Another important function of HAS1 is its role in the regulation of inflammation. HAS1 has been shown to play a key role in the regulation of the immune response and has been shown to interact with a variety of immune cells and molecules, including T cells, natural killer cells, and inflammation-promoting molecules.

In addition to its role in cellular and inflammatory processes, HAS1 is also thought to be involved in the regulation of the blood-brain barrier. This is the barrier that separates the brain from the blood and is thought to play a key role in the regulation of brain function. HAS1 has been shown to interact with the protein PDZ1, which is a protein that is involved in the formation of the blood-brain barrier, and has been shown to play a role in the regulation of brain development and function.

Despite its importance in a variety of cellular and biological processes, HAS1 is still not well understood, and much more research is needed to fully understand its role in the regulation of cellular and biological processes. In the future, HAS1 is likely to be a drug target and may also be used as a biomarker for a variety of diseases.

Protein Name: Hyaluronan Synthase 1

Functions: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate (By similarity)

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