HDC: A Drug Target / Disease Biomarker (G3067)

Target Name: HDC

NCBI ID: G3067

HDC: A Drug Target / Disease Biomarker

Histidine decarboxylase (HDC) is a enzyme that plays a critical role in the regulation of protein function in the body. It is a key enzyme in the histidine pathway, which is involved in the regulation of various cellular processes such as cell signaling, inflammation, and tissue repair. HDC is also involved in the metabolism of histidine, a crucial amino acid that is found in many proteins and plays a central role in many cellular processes.

HDC is a protein that is expressed in many different tissues and cells in the body. It is primarily found in the cytoplasm of cells, but is also found in the nucleus and other organelles. HDC is a monomeric protein, which means that it is composed of a single polypeptide chain. It has a molecular weight of approximately 18 kDa and a pre-calculated pI of 6.8.

HDC is involved in the regulation of a wide range of cellular processes that are critical for the survival and proper functioning of cells. One of its key functions is the regulation of the histidine pathway, which is involved in the regulation of various cellular processes such as cell signaling, inflammation, and tissue repair. HDC is the enzyme that catalyzes the conversion of histidine to its active form, histidine monophosphate (HMP).

HMP is a critical molecule that is involved in many cellular processes. It plays a central role in the regulation of protein function, as it can interact with a wide range of protein substrates. HMP can also serve as a signaling molecule, as it can interact with various signaling proteins and play a role in the regulation of cellular signaling pathways.

Another function of HDC is the metabolism of histidine, which is a crucial amino acid that is found in many proteins and plays a central role in many cellular processes. HDC is involved in the conversion of histidine to its stable form, histidine dimer (HDM), which is a critical precursor for the synthesis of histidine monohydrochloride (HCHQ), a molecule that is involved in the regulation of various cellular processes.

HDC is also involved in the regulation of the levels of histidine in the body. It is able to regulate the concentration of histidine in the cytoplasm and has been shown to play a role in the regulation of histidine levels in various tissues and cells. This function is important for the proper functioning of cells and is a potential drug target for the development of histidine-based therapeutics.

In conclusion, HDC is a critical enzyme that plays a wide range of roles in the regulation of cellular processes in the body. Its functions as a drug target or biomarker make it an attractive target for the development of new therapies. Further research is needed to fully understand the mechanisms of HDC's role in the regulation of cellular processes and to develop effective strategies for the treatment of histidine-related diseases.

Protein Name: Histidine Decarboxylase

Functions: Catalyzes the biosynthesis of histamine from histidine

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