HEPH: Chromatin Remodeling and Cancer Development (G9843)

Target Name: HEPH

NCBI ID: G9843

HEPH: Chromatin Remodeling and Cancer Development

HEPH (Histone acetyl transferase of pH 9) is a gene that encodes a protein known as HEPH, which is involved in the process of chromatin remodeling. Chromatin remodeling is a critical process that occurs during the development and progression of cancer, and it is characterized by the alteration of the structure and composition of chromosomes.

HEPH is a key player in this process, as it plays a role in the transfer of histones from the microtubules of the chromosomes to their centromeres. Histones are small, positively charged proteins that play a structural role in organizing DNA in the nucleus of the cell . They are also involved in the regulation of gene expression, and their levels can vary depending on the stage of the cell cycle and the response to different stimuli.

HEPH is a 22-kDa protein that consists of 158 amino acid residues. It is expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. It is highly conserved, with a calculated pI of 4.71 and a predicted localization in the cytoplasm of cells.

HEPH is involved in the process of chromatin remodeling, which is the addition of genetic information from the cell's DNA to its chromatin. This process is critical for the development and progression of cancer, as it allows the cells to accumulate genetic mutations that can lead to the formation of tumors.

One of the key functions of HEPH is its role in the transfer of histones from the microtubules of the chromosomes to their centromeres. Histones are small, positively charged proteins that play a structural role in organizing DNA in the nucleus of the cell. They are also involved in the regulation of gene expression, and their levels can vary depending on the stage of the cell cycle and the response to different stimuli.

HEPH is a 22-kDa protein that consists of 158 amino acid residues. It is expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. It is highly conserved, with a calculated pI of 4.71 and a predicted localization in the cytoplasm of cells.

HEPH is involved in the process of chromatin remodeling, which is the addition of genetic information from the cell's DNA to its chromatin. This process is critical for the development and progression of cancer, as it allows the cells to accumulate genetic mutations that can lead to the formation of tumors.

One of the key functions of HEPH is its role in the transfer of histones from the microtubules of the chromosomes to their centromeres. Histones are small, positively charged proteins that play a structural role in organizing DNA in the nucleus of the cell. They are also involved in the regulation of gene expression, and their levels can vary depending on the stage of the cell cycle and the response to different stimuli.

HEPH is a 22-kDa protein that consists of 158 amino acid residues. It is expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. It is highly conserved, with a calculated pI of 4.71 and a predicted localization in the cytoplasm of cells.

HEPH is involved in the process of chromatin remodeling, which is the addition of genetic information from the cell's DNA to its chromatin. This process is critical for the development and progression of cancer, as it allows the cells to accumulate genetic mutations that can lead to the formation of tumors.

One of the key functions of HEPH is its role in the transfer of histones from the microtubules of the chromosomes to their centromeres. Histones are small, positively charged proteins that play a structural role in organizing DNA in the nucleus of the cell. They are also involved in the regulation of gene expression, and their levels can vary depending on the stage of the cell cycle and the response to different stimuli.

HEPH is a 22-kDa protein that consists of 158 amino acid residues. It is expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. It is highly conserved, with a calculated pI of 4.71 and a predicted localization in the cytoplasm of cells.

In conclusion, HEPH is a gene that encodes a protein involved in the process of chromatin remodeling. It is highly conserved and expressed in a variety of tissues, including muscle, heart, brain, and cancer cells. Its function is crucial in the development and progression of cancer, as it allows the cells to accumulate genetic mutations that can lead to the formation of tumors. Further research is needed to fully understand the role of HEPH in this process and to develop effective strategies for the treatment of cancer.

Protein Name: Hephaestin

Functions: May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1

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