Target Name: HAND2
NCBI ID: G9464
Other Name(s): dHAND | basic helix-loop-helix transcription factor HAND2 | HAND2_HUMAN | FLJ16260 | dHand | MGC125304 | OTTHUMP00000218982 | Heart and neural crest derivatives expressed 2 | Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2 | Class A basic helix-loop-helix protein 26 | Thing2 | MGC125303 | Heart- and neural crest derivatives-expressed protein 2 | bHLHa26 | class A basic helix-loop-helix protein 26 | Hed | Basic helix-loop-helix transcription factor HAND2 | DHAND2 | heart and neural crest derivatives expressed 2 | deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2

Hand2: A Protein Involved in Nervous System Development and Maintenance

Hand2 (dHAND) is a protein that is expressed in the human hand and is involved in the development and maintenance of the nervous system. It is a member of the tight gene family, which includes proteins that are involved in various cellular processes, including cell signaling and tissue structure.

One of the unique features of Hand2 is its ability to interact with other proteins that are involved in the development and maintenance of the nervous system. This interaction is important for the proper functioning of the nervous system and is a potential drug target for the development of new treatments for a variety of neurological conditions.

Research has shown that Hand2 plays a role in the development and maintenance of the nervous system by helping to ensure the proper structure and function of the nervous system cells. This includes the formation of new neurons and the maintenance of the integrity of the nervous system cells.

In addition to its role in the nervous system, Hand2 has also been shown to play a role in the development and maintenance of various tissues and organs. This includes the skin, heart, and blood vessels.

The research on Hand2 has led to the potential development of new treatments for a variety of neurological conditions. For example, studies have shown that Hand2 may be a potential drug target for the development of neurodegenerative conditions, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential use as a drug target, Hand2 has also been shown to be involved in the development and maintenance of various physiological processes in the body. This includes the regulation of pain and the immune response.

Overall, Hand2 is a protein that is involved in a variety of cellular processes that are important for the development and maintenance of the nervous system and other tissues and organs. Its potential as a drug target makes it an attractive target for researchers to explore for the development of new treatments for a variety of neurological conditions.

Protein Name: Heart And Neural Crest Derivatives Expressed 2

Functions: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity)

More Common Targets

HAND2-AS1 | HAO1 | HAO2 | HAO2-IT1 | HAP1 | HAPLN1 | HAPLN2 | HAPLN3 | HAPLN4 | HAPSTR1 | HAR1A | HAR1B | HARBI1 | HARS1 | HARS2 | HAS1 | HAS2 | HAS2-AS1 | HAS3 | HASPIN | HAT1 | HAUS1 | HAUS1P1 | HAUS2 | HAUS3 | HAUS4 | HAUS5 | HAUS6 | HAUS7 | HAUS8 | HAVCR1 | HAVCR1P1 | HAVCR2 | HAX1 | HAX1P1 | HBA1 | HBA2 | HBAP1 | HBB | HBBP1 | HBD | HBE1 | HBEGF | HBG1 | HBG2 | HBM | HBO1 complex | HBP1 | HBQ1 | HBS1L | HBZ | HBZP1 | HCAR1 | HCAR2 | HCAR3 | HCCAT5 | HCCS | HCFC1 | HCFC1R1 | HCFC2 | HCG11 | HCG14 | HCG15 | HCG17 | HCG18 | HCG20 | HCG21 | HCG22 | HCG23 | HCG25 | HCG26 | HCG27 | HCG4 | HCG4B | HCG4P11 | HCG4P3 | HCG4P5 | HCG4P8 | HCG9 | HCGVIII-2 | HCK | HCLS1 | HCN1 | HCN2 | HCN3 | HCN4 | HCP5 | HCRT | HCRTR1 | HCRTR2 | HCST | HDAC1 | HDAC10 | HDAC11 | HDAC11-AS1 | HDAC1P1 | HDAC2 | HDAC2-AS2 | HDAC3 | HDAC4