Target Name: GYS1
NCBI ID: G2997
Other Name(s): GYS1_HUMAN | GYS1 variant 1 | glycogen synthase 1 (muscle) | Glycogen [starch] synthase, muscle (isoform 1) | glycogen synthase 1 | Glycogen [starch] synthase, muscle | Glycogen(starch) synthase 1 | GYS | GSY | Glycogen synthase 1 (muscle) | Glycogen synthase 1, transcript variant 1

GYS1: Multi-Functional Protein Regulating Neurotransmission, Signaling, Cell Adhesion, Inflammation

GYS1 (GYS1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, lungs, and kidneys. It is a member of the GYNASMase family, which is a group of transmembrane proteins that regulate intracellular signaling pathways. GYS1 has been shown to play a role in the regulation of cellular processes that are important for brain development, function, and disease.

One of the key functions of GYS1 is its role in the regulation of neurotransmitter release from nerve axons. GYS1 is involved in the catalytic mechanism of the neurotransmitter release process, which involves the breakdown of the neurotransmitter synapse and the release of the neurotransmitter into the cytosol. This process is critical for the proper functioning of the nervous system and is implicated in a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression.

In addition to its role in neurotransmitter release, GYS1 is also involved in the regulation of intracellular signaling pathways. It has been shown to play a role in the regulation of ion channels, which are responsible for the flow of electrical current through the cell membrane. GYS1 has been shown to modulate the activity of these channels, which can affect the movement of charged particles, such as calcium ions, into and out of the cells. This regulation is important for the proper functioning of many cellular processes, including muscle contractions, nerve function, and blood pressure.

GYS1 is also involved in the regulation of cell adhesion. It is a member of the cadherin family of transmembrane proteins, which are involved in the formation of tight junctions between adjacent cells. GYS1 is shown to play a role in the regulation of cadherin interactions and is implicated in the development of cancer.

In addition to its roles in neurotransmission, intracellular signaling, and cell adhesion, GYS1 is also involved in the regulation of inflammation. It is a member of the NF-kappa-B signaling pathway, which is a critical pathway involved in the regulation of inflammation and immune responses. GYS1 has been shown to play a role in the regulation of NF-kappa-B signaling and is implicated in the development of many inflammatory diseases, including arthritis, asthma, and heart disease.

GYS1 is also involved in the regulation of cellular stress responses. It is a member of the p62 complex, which is responsible for the regulation of cellular stress responses. GYS1 has been shown to play a role in the regulation of p62 activity and is implicated in the development of many cellular stress responses, including neurodegenerative diseases.

GYS1 is also involved in the regulation of mitochondrial function. It is a member of the mitochondrial inner membrane protein family and is shown to play a role in the regulation of mitochondrial fusion and fission. This regulation is important for the proper functioning of the mitochondria, which are responsible for the production of energy in the cell.

In conclusion, GYS1 is a protein that is involved in a number of important cellular processes in the human body. Its functions include the regulation of neurotransmission, intracellular signaling pathways, cell adhesion, inflammation, cellular stress responses, and mitochondrial function. GYS1 is a potential drug target and could be a valuable tool for the development of new treatments for a number of neurological and psychiatric disorders.

Protein Name: Glycogen Synthase 1

Functions: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan

More Common Targets

GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT | H2AZ2 | H2AZ2-DT | H2AZP2 | H2BC1 | H2BC10 | H2BC11 | H2BC12 | H2BC12L | H2BC13 | H2BC14 | H2BC15 | H2BC17 | H2BC18 | H2BC20P | H2BC21 | H2BC26 | H2BC27P | H2BC3 | H2BC4 | H2BC5 | H2BC6 | H2BC7 | H2BC8 | H2BC9 | H2BP1 | H2BP2 | H2BP3 | H2BW1 | H2BW2 | H2BW4P | H3-3A | H3-3B | H3-4 | H3-5 | H3-7 | H3C1 | H3C10 | H3C11 | H3C12 | H3C13 | H3C14 | H3C15 | H3C2 | H3C3 | H3C4 | H3C6 | H3C7 | H3C8 | H3P16 | H3P36 | H3P37 | H3P44 | H3P5 | H3P6 | H4C1