Target Name: GTPBP4
NCBI ID: G23560
Other Name(s): GTP binding protein 4 | nucleolar GTP-binding protein 1 | FLJ10686 | Chronic renal failure gene protein | NOG1 | GTPB4_HUMAN | GTP-binding protein | chronic renal failure gene protein | NGB | FLJ10690 | FLJ39774 | GTP-binding protein 4 | G protein-binding protein CRFG | Nucleolar GTP-binding protein 1 | CRFG | GTP-binding protein NGB | Chronic renal failure

GTPBP4: A Protein in Many Cellular Processes

GTPBP4 is a protein that is found in all living cells. It plays a critical role in the intracellular signaling pathway known as the G-protein-coupled receptor (GPCR) signaling pathway. This pathway is involved in many cellular processes, including but not limited to cell survival, growth, and metabolism. Mutations in the GTPBP4 gene have been linked to a variety of diseases, including cardiovascular disease, neurodegenerative diseases, and reproductive disorders. As a result, GTPBP4 has become a focus of research in the field of pharmacology, with a goal of developing new treatments for these diseases.

GTPBP4 is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. GPCR signaling pathways are involved in many cellular processes, including but not limited to cell survival, growth, and metabolism. The GTPBP4 protein is a key component of these signaling pathways, as it plays a critical role in the regulation of GPCR signaling.

GTPBP4 is involved in the regulation of many different GPCR signaling pathways. For example, it has been shown to play a role in the regulation of neurotransmitter signaling, which is involved in the function of the nervous system. GTPBP4 has also been shown to play a role in the regulation of ion channels, which are involved in the flow of electrical current through the cell membrane. Additionally, GTPBP4 has been shown to play a role in the regulation of cell adhesion, which is involved in the formation of tight junctions and adherens junctions, which are important for the proper functioning of cells.

GTPBP4 is also involved in the regulation of many different cellular processes that are critical for the survival and growth of cells. For example, it has been shown to play a role in the regulation of cell proliferation, which is the process by which cells grow and divide. GTPBP4 has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die when they are no longer needed. Additionally, GTPBP4 has been shown to play a role in the regulation of cell migration, which is the process by which cells move from one location to another in the body.

GTPBP4 has also been shown to play a role in the regulation of the immune system. For example, it has been shown to play a role in the regulation of T cell development and function. GTPBP4 has also been shown to play a role in the regulation of inflammation, which is a critical immune response to the presence of foreign substances in the body.

In conclusion, GTPBP4 is a critical protein that plays a critical role in many cellular processes that are involved in the survival and growth of cells. As a result, GTPBP4 has become a focus of research in the field of pharmacology, with a goal of developing new treatments for diseases that are associated with the regulation of GTPBP4. Further research is needed to fully understand the role of GTPBP4 in cellular signaling and to develop new treatments based on this understanding.

Protein Name: GTP Binding Protein 4

Functions: Involved in the biogenesis of the 60S ribosomal subunit (PubMed:32669547). Acts as TP53 repressor, preventing TP53 stabilization and cell cycle arrest (PubMed:20308539)

More Common Targets

GTPBP6 | GTPBP8 | GTSCR1 | GTSE1 | GTSE1-DT | GTSF1 | GTSF1L | Guanine nucleotide-binding protein G(t) complex | Guanylate cyclase | Guanylate kinase (isoform b) | GUCA1A | GUCA1B | GUCA1C | GUCA2A | GUCA2B | GUCD1 | GUCY1A1 | GUCY1A2 | GUCY1B1 | GUCY1B2 | GUCY2C | GUCY2D | GUCY2EP | GUCY2F | GUCY2GP | GUF1 | GUK1 | GULOP | GULP1 | GUSB | GUSBP1 | GUSBP11 | GUSBP12 | GUSBP14 | GUSBP15 | GUSBP17 | GUSBP2 | GUSBP3 | GUSBP4 | GUSBP5 | GUSBP8 | GVINP1 | GVQW3 | GXYLT1 | GXYLT1P3 | GXYLT1P4 | GXYLT1P6 | GXYLT2 | GYG1 | GYG2 | GYPA | GYPB | GYPC | GYPE | GYS1 | GYS2 | GZF1 | GZMA | GZMB | GZMH | GZMK | GZMM | H1-0 | H1-1 | H1-10 | H1-10-AS1 | H1-2 | H1-3 | H1-4 | H1-5 | H1-6 | H1-7 | H1-8 | H1-9P | H19 | H19-ICR | H2AB1 | H2AB2 | H2AB3 | H2AC1 | H2AC11 | H2AC12 | H2AC13 | H2AC14 | H2AC15 | H2AC16 | H2AC17 | H2AC18 | H2AC20 | H2AC21 | H2AC25 | H2AC3P | H2AC4 | H2AC6 | H2AC7 | H2AJ | H2AP | H2AX | H2AZ1 | H2AZ1-DT