EXOC7: A Protein Associated with Cancer and Neurodegenerative Diseases

Target Name: EXOC7

NCBI ID: G23265

EXOC7: A Protein Associated with Cancer and Neurodegenerative Diseases

EXOC7 (EX070) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. Its full name is Exonuclease VII, and it is a member of the DNA-protein extrusion family. This protein is of interest as a potential drug target or biomarker due to its unique structure and the diseases it is associated with.

EXOC7 is a 14 kDa protein that is expressed in the brain, heart, and liver. It is synthesized from the last exon of the gene EXO7, which is located on chromosome 17. EXOC7 is composed of a 110 amino acid long protein chain that contains a unique N-terminal region that is involved in its stability and functions.

One of the unique features of EXOC7 is its ability to cleave double-stranded DNA at specific sites. This property is crucial for its role in the development and progression of various diseases, including cancer. EXOC7 has been shown to play a role in the regulation of gene expression, and it is thought to contribute to the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

EXOC7 is also associated with a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, EXOC7 has been shown to be overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that it may be a promising target for cancer therapies. Additionally, EXOC7 has been implicated in a number of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This suggests that it may also be a useful biomarker for these diseases.

EXOC7 is also of interest as a potential drug target due to its unique structure and the diseases it is associated with. Its N-terminal region, which is involved in its stability and functions, makes it a potential target for small molecules or antibodies that can modulate its activity. Additionally, its role in the regulation of gene expression and cellular processes makes it a potential target for drugs that can modulate gene expression or cell signaling pathways.

In conclusion, EXOC7 is a protein that is expressed in various tissues of the body and is associated with a number of diseases, including cancer and neurodegenerative disorders. Its unique structure and the diseases it is associated with make it a potential drug target or biomarker. Further research is needed to fully understand its role in these diseases and to develop effective therapies that can modulate its activity.

Protein Name: Exocyst Complex Component 7

Functions: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity). It is required for neuron survival and plays an essential role in cortical development (By similarity)

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