FABP5L11: A Potential Drug Target and Biomarker (G266699)

Target Name: FABP5P11

NCBI ID: G266699

Other Name(s): FABP5L11 | fatty acid binding protein 5 pseudogene 11 | Fatty acid binding protein 5 pseudogene 11 | FABP5P1

FABP5L11: A Potential Drug Target and Biomarker

FABP5L11, also known as FABP5-L11, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its unique structure and expression pattern have made it an attractive target for drug development, particularly for the treatment of neurodegenerative diseases.

The FABP5L11 protein is a member of the FABP family, which includes a variety of proteins that are involved in the regulation of cell survival and growth. The FABP5L11 protein is characterized by its N-terminus, which is rich in amino acids that are involved in the formation of a distinct protein structure called an N-terminal intramolecular cleavage (N-terminus) domain. This domain is known to be involved in the protein's stability and localization to specific cellular compartments.

FABP5L11 has been shown to play a role in the development and progression of a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It has been shown to be expressed in the brains of individuals with these conditions, and to be involved in the formation of neurofibrillary tangles and other hallmark pathological features of these diseases.

In addition to its potential role in the development of neurodegenerative diseases, FABP5L11 has also been shown to be a potential biomarker for these conditions. The protein is expressed in the brain and other tissues of individuals with neurodegenerative diseases, and its levels have been shown to be altered in these conditions. This suggests that FABP5L11 may be a useful diagnostic or predictive marker for these diseases.

FABP5L11 has also been shown to be involved in the regulation of cellular processes that are important for brain function. For example, studies have shown that FABP5L11 is involved in the regulation of the trafficking of brain-derived neurotrophic factor (BDNF) to its target, the protein TrkB. This suggests that FABP5L11 may be a target for drugs that are designed to promote brain health and protect against neurodegeneration.

In conclusion, FABP5L11 is a protein that has been shown to play a role in the development and progression of a variety of neurodegenerative diseases. Its unique structure and expression pattern, as well as its involvement in the regulation of cellular processes that are important for brain function, make it an attractive target for drug development. Further research is needed to fully understand the role of FABP5L11 in these diseases and to develop effective treatments.

Protein Name: Fatty Acid Binding Protein 5 Pseudogene 11

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