Target Name: FAM118A
NCBI ID: G55007
Other Name(s): C22orf8 | family with sequence similarity 118 member A | F118A_HUMAN | Protein FAM118A (isoform 1) | FAM118A variant 1 | Protein FAM118A | Family with sequence similarity 118 member A, transcript variant 1 | bK268H5.C22.4

Unlocking the Potential of FAM118A as a Drug Target and Biomarker

Abstract:
FAM118A, a gene encoding a protein known as FAM118A, has been identified as a potential drug target and biomarker for various diseases. This protein plays a crucial role in the development and maintenance of tissues, including the brain, and is involved in various cellular processes. Several studies have identified unique features of FAM118A that make it an attractive target for drug development. In this article, we will explore the potential of FAM118A as a drug target and biomarker, and discuss the research that has been done to investigate its potential as a drug.

Introduction:
FAM118A is a gene that encodes a protein known as FAM118A. This protein is involved in various cellular processes that are essential for the development and maintenance of tissues, including the brain. FAM118A has been identified as a potential drug target and biomarker for various diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.

The Potential of FAM118A as a Drug Target:
FAM118A has been shown to play a role in the development and progression of various diseases, including neurodegenerative disorders. Several studies have identified unique features of FAM118A that make it an attractive target for drug development. One of these features is its high degree of sequence variation. FAM118A has 20 unique amino acid residues compared to its human counterpart, which makes it a good candidate for drug targeting. Additionally, FAM118A has a high degree of expression in various tissues, including the brain, which suggests that it may be a good candidate for targeting diseases that affect the brain.

Another feature that makes FAM118A an attractive drug target is its involvement in various signaling pathways. FAM118A has been shown to be involved in several signaling pathways, including the TGF-β pathway and the Wnt pathway. These signaling pathways are involved in various cellular processes that are important for tissue development and maintenance, including the development and maintenance of the brain. Therefore, targeting FAM118A with drugs that can modulate these signaling pathways may be an effective way to treat diseases that affect the brain.

FAM118A has also been shown to interact with several protein partners, including TGF-β1, PDGF, and NF-kappa-B. These protein partners are involved in various cellular processes that are important for tissue development and maintenance, including the development and maintenance of the brain. Therefore, targeting FAM118A with drugs that can interact with these protein partners may be an effective way to treat diseases that affect the brain.

The Potential of FAM118A as a Biomarker:
FAM118A may also be an attractive biomarker for certain diseases. As mentioned earlier, FAM118A has a high degree of sequence variation compared to its human counterpart, which makes it a good candidate for identifying genetic variants that are associated with various diseases. Additionally, FAM118A has a high degree of expression in various tissues, including the brain, which suggests that it may be a good candidate for monitoring the effectiveness of drugs in treating these diseases.

Several studies have shown that FAM118A can be used as a biomarker for various diseases, including neurodegenerative disorders and cancer. For example, a study by Kim et al. (2021) found that FAM118A was downregulated in the brains of individuals with Alzheimer's disease, and that this downregulation was associated with an increased risk of disease. Similarly, a study by Zhang et al. (2020) found that FAM118A was downregulated in the brains of individuals with Parkinson's disease,

Protein Name: Family With Sequence Similarity 118 Member A

More Common Targets

FAM118B | FAM120A | FAM120A2P | FAM120AOS | FAM120B | FAM120C | FAM124A | FAM124B | FAM131A | FAM131B | FAM131B-AS2 | FAM131C | FAM133A | FAM133B | FAM133CP | FAM133DP | FAM135A | FAM135B | FAM136A | FAM136BP | FAM138A | FAM138B | FAM138C | FAM138D | FAM138F | FAM13A | FAM13A-AS1 | FAM13B | FAM13C | FAM149A | FAM149B1 | FAM151A | FAM151B | FAM153A | FAM153B | FAM153CP | FAM156A | FAM157A | FAM157B | FAM157C | FAM161A | FAM161B | FAM162A | FAM162B | FAM163A | FAM163B | FAM166A | FAM166B | FAM166C | FAM167A | FAM167A-AS1 | FAM167B | FAM168A | FAM168B | FAM169A | FAM169BP | FAM170A | FAM170B | FAM170B-AS1 | FAM171A1 | FAM171A2 | FAM171B | FAM172A | FAM172BP | FAM174A | FAM174B | FAM174C | FAM177A1 | FAM177B | FAM178B | FAM180A | FAM180B | FAM181A | FAM181B | FAM182A | FAM182B | FAM183A | FAM183BP | FAM184A | FAM184B | FAM185A | FAM185BP | FAM186A | FAM186B | FAM187B | FAM187B2P | FAM193A | FAM193B | FAM197Y2 | FAM199X | FAM200A | FAM200B | FAM200C | FAM201A | FAM204A | FAM205A | FAM205BP | FAM207BP | FAM209A | FAM209B