Target Name: MTUS2
NCBI ID: G23281
Other Name(s): cardiac zipper protein | Cardiac zipper protein | Microtubule-associated tumor suppressor candidate 2 isoform a | microtubule plus-end tracking protein TIP150 | CAZIP | KIAA0774 | microtubule associated scaffold protein 2 | tracking protein of 150 kDa | MTUS2 variant 1 | ICIS | Microtubule associated scaffold protein 2, transcript variant 1 | TIP150 | MTUS2_HUMAN | microtubule associated tumor suppressor candidate 2 | +TIP of 150 kDa | Microtubule-associated tumor suppressor candidate 2 | Microtubule plus-end tracking protein TIP150 | Tracking protein of 150 kDa

MTUS2: A Potential Drug Target and Biomarker for Cardiac Zipper Protein

Heart disease is a leading cause of morbidity and mortality worldwide, accounting for approximately 17% of all deaths worldwide. One of the major cardiac proteins that is involved in cardiac function and development is cardiac zipper protein (CZP). CZP plays a crucial role in the regulation of cell proliferation, apoptosis, and cardiac function. Unfortunately, CZP has also been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Therefore, the study of CZP and its potential drug targets is of great interest.

MTUS2, a member of the Zip family of proteins, is a unique protein that has been identified as a potential drug target and biomarker for CZP. In this article, we will discuss the structure and function of MTUS2, its potential drug targets, and its potential as a biomarker for cardiac diseases.

Structure and Function of MTUS2

MTUS2 is a 25 kDa protein that belongs to the Zip family of proteins. The Zip family of proteins consists of several similar proteins, including ZIP/TAZ, ZAP, and ZPT. These proteins share a conserved catalytic core and a characteristic Z-type dimerization pattern. MTUS2 has a unique N-terminal region that contains a putative nucleotide-binding oligomerization (NBO) domain and a C-terminal region that contains a Z-type dimerization domain.

The NBO domain is a unique feature that is found in several Zip proteins, including MTUS2. This domain is involved in the regulation of nucleotide binding and can function as a nucleotide-binding oligomerization (NBO) domain. This domain has been shown to play a role in the regulation of cellular processes, including cell proliferation, apoptosis, and transcriptional regulation.

The C-terminal Z-type dimerization domain is a unique feature that is found in several Zip proteins, including MTUS2. This domain is involved in the regulation of protein-protein interactions (PPI) and has been shown to play a role in the regulation of cellular processes, including cell signaling, protein folding, and stability.

Potential Drug Targets of MTUS2

MTUS2 has several potential drug targets that could be exploited for the treatment of cardiac diseases. One of the potential drug targets of MTUS2 is the regulation of cellular proliferation. MTUS2 has been shown to play a role in the regulation of cell proliferation and has been shown to be involved in the regulation of cell cycle progression. Therefore, inhibitors of MTUS2 could be useful for the treatment of cardiac diseases, such as cancer, neurodegenerative diseases, and autoimmune diseases.

Another potential drug target of MTUS2 is the regulation of cellular apoptosis. MTUS2 has been shown to play a role in the regulation of cellular apoptosis and has been shown to be involved in the regulation of cell death. Therefore, inhibitors of MTUS2 could be useful for the treatment of cardiac diseases, such as cancer, neurodegenerative diseases, and autoimmune diseases.

In addition to its potential drug targets, MTUS2 has also been shown to have potential as a biomarker for cardiac diseases. MTUS2 has been shown to be involved in the regulation of cellular processes, including cell signaling, protein folding, and stability. Therefore, MTUS2 has the potential to serve as a biomarker for cardiac diseases, including heart failure, arrhythmia, and sudden cardiac death.

Potential Applications of MTUS2 as a Drug Target or Biomarker

The study of MTUS2 has significant potential applications in the treatment of cardiac diseases. As a potential drug target, MTUS2 has been shown to be involved in the regulation of

Protein Name: Microtubule Associated Scaffold Protein 2

Functions: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip

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MTUS2-AS1 | MTVR2 | MTX1 | MTX2 | MTX3 | mu-Calpain (calpain 1) | MUC1 | MUC12 | MUC13 | MUC15 | MUC16 | MUC17 | MUC19 | MUC2 | MUC20 | MUC20P1 | MUC21 | MUC22 | MUC3A | MUC3B | MUC4 | MUC5AC | MUC5B | MUC6 | MUC7 | MUC8 | Mucin | MUCL1 | MUCL3 | MUL1 | Multisubunit histone acetyltransferase complex | MUPP | MUS81 | Muscarinic Acetylcholine Receptor (mAChR) | MUSK | MUSTN1 | MUTYH | MVB12A | MVB12B | MVD | MVK | MVP | MX1 | MX2 | MXD1 | MXD3 | MXD4 | MXI1 | MXRA5 | MXRA5Y | MXRA7 | MXRA8 | MYADM | MYADML | MYADML2 | MYB | MYBBP1A | MYBL1 | MYBL2 | MYBPC1 | MYBPC2 | MYBPC3 | MYBPH | MYBPHL | MYC | MYCBP | MYCBP2 | MYCBP2-AS1 | MYCBPAP | MYCL | MYCL-AS1 | MYCLP1 | MYCN | MYCNOS | MYCNUT | MYCT1 | MYD88 | MYDGF | MYEF2 | Myelin Protein | MYEOV | MYF5 | MYF6 | MYG1 | MYH1 | MYH10 | MYH11 | MYH13 | MYH14 | MYH15 | MYH16 | MYH2 | MYH3 | MYH4 | MYH6 | MYH7 | MYH7B | MYH8 | MYH9 | MYHAS