DPY19L1: A Potential Drug Target for Cancer, Autoimmune Diseases and Cardiac Dysfunction

Target Name: DPY19L1

NCBI ID: G23333

DPY19L1: A Potential Drug Target for Cancer, Autoimmune Diseases and Cardiac Dysfunction

DPY19L1 (D19L1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and muscle. It is a member of the tyrosine kinase family and is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and survival.

One of the unique features of DPY19L1 is its ability to interact with multiple protein substrates, including casein kinase 2 (CK-2), which is a protein that is involved in the regulation of cellular processes such as cell adhesion, migration, and invasion. This interaction between DPY19L1 and CK-2 has been identified as a potential drug target for the treatment of various diseases, including cancer.

In addition to its role in cell signaling, DPY19L1 is also thought to play a role in the regulation of inflammation. It has been shown to be involved in the recruitment of immune cells to sites of infection or inflammation, which could make it a potential target for the treatment of autoimmune diseases.

DPY19L1 is also expressed in various tissues of the body that are involved in the production of antibodies, including the plasma cells of B cells. This suggests that it may be involved in the regulation of the immune response, which could make it a potential target for the treatment of autoimmune diseases.

Furthermore, DPY19L1 is also expressed in the heart, which suggests that it may be involved in the regulation of cardiac function. This is supported by the fact that DPY19L1 has been shown to be involved in the regulation of contractility in the heart, as well as in the regulation of the heart's electrical activity.

In conclusion, DPY19L1 is a protein that is expressed in various tissues of the human body and is involved in a wide range of cellular processes. Its interaction with multiple protein substrates, including casein kinase 2, makes it a potential drug target for the treatment of various diseases, including cancer, autoimmune diseases, and cardiac dysfunction. Further research is needed to fully understand the role of DPY19L1 in cellular signaling and to determine its potential as a drug target.

Protein Name: Dpy-19 Like C-mannosyltransferase 1

Functions: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins

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