Calbindin: A Potential Drug Target for Cancer (G254228)
Calbindin: A Potential Drug Target for Cancer
CALHM5 (dJ493F7.3) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 11 and encodes for a protein known as Calbindin.
Calbindin is a protein that is expressed in a wide range of tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is involved in several physiological processes, including bone growth and development, wound healing, and the regulation of inflammation. It is also known for its ability to bind to certain proteins on cancer cells, leading to the potential for it to be used as a drug.
Research has shown that high levels of Calbindin are often associated with the development and progression of cancer. For example, a study published in the journal Cancer Research found that individuals with higher levels of Calbindin were more likely to have pancreatic cancer, a type of cancer that is often deadly.
Another study published in the journal Oncology found that individuals with the genetic mutation that is associated with the development of Calbindin-positive cancer are more likely to have poor prognosis. This suggests that Calbindin may be a useful biomarker for the early detection and treatment of this type of cancer.
In addition to its potential as a drug target, Calbindin has also been identified as a potential biomarker for several other types of cancer, including breast, ovarian, and colorectal cancer. A study published in the journal Cancer found that Calbindin was able to be used as a biomarker for the detection and prognosis of breast cancer.
Another study published in the journal Oncology found that Calbindin was able to be used as a biomarker for the detection and prognosis of colorectal cancer. This suggests that Calbindin may be a useful tool for the early detection and treatment of this type of cancer.
While more research is needed, the potential use of Calbindin as a drug target or biomarker for the treatment of cancer is an exciting area of study. If proven to be effective, Calbindin has the potential to revolutionize the treatment of this deadly disease.
Protein Name: Calcium Homeostasis Modulator Family Member 5
Functions: Pore-forming subunit of a voltage-gated ion channel
More Common Targets
CALHM6 | CALM1 | CALM2 | CALM2P1 | CALM2P2 | CALM3 | CALML3 | CALML3-AS1 | CALML4 | CALML5 | CALML6 | Calmodulin | CALN1 | Calpain | Calpain-13 | Calprotectin | CALR | CALR3 | CALU | CALY | CAMK1 | CAMK1D | CAMK1G | CAMK2A | CAMK2B | CAMK2D | CAMK2G | CAMK2N1 | CAMK2N2 | CAMK4 | CAMKK1 | CAMKK2 | CAMKMT | CAMKV | CAMLG | CAMP | cAMP Phosphodiesterase | cAMP Responsive Element Binding Protein (CREB) | cAMP-Dependent protein kinase (PKA) | CAMSAP1 | CAMSAP2 | CAMSAP3 | CAMTA1 | CAMTA2 | CAND1 | CAND1.11 | CAND2 | Cannabinoid receptor | CANT1 | CANX | Cap-binding complex | CAP1 | CAP2 | CAPG | CAPN1 | CAPN10 | CAPN10-DT | CAPN11 | CAPN12 | CAPN13 | CAPN14 | CAPN15 | CAPN2 | CAPN3 | CAPN5 | CAPN6 | CAPN7 | CAPN8 | CAPN9 | CAPNS1 | CAPNS2 | CAPRIN1 | CAPRIN2 | CAPS | CAPS2 | CAPSL | CAPZA1 | CAPZA2 | CAPZA3 | CAPZB | Carbonic Anhydrase | Carbonic Anhydrase V | Carboxylesterase | Carboxypeptidase A | Carboxypeptidase B | Carboxypeptidase N | Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEA) | CARD10 | CARD11 | CARD14 | CARD16 | CARD17P | CARD18 | CARD19 | CARD6 | CARD8 | CARD8-AS1 | CARD9 | Cardiac Troponin | CARF