Understanding CANP10: A Potential Drug Target for Neurological Disorders

Target Name: CAPN10

NCBI ID: G11132

Understanding CANP10: A Potential Drug Target for Neurological Disorders

CAPN10 (CANP 10) is a protein that is expressed in the brain and is involved in the regulation of cell death. It is a potential drug target (or biomarker) that can be targeted with small molecules to treat various neurological disorders.

The CANP10 protein is composed of 10 subunits that are located in different parts of the brain. It is expressed in the cerebral cortical cortical and subcortical regions, and it is involved in the regulation of cell death, neurodegeneration, and neuroinflammation.

One of the CANP10 subunits is called CANP10-1, which is a scaffold protein that is involved in the formation of memory and learning. CANP10-1 has been shown to play a role in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

Another subunit of CANP10 is called CANP10-2, which is involved in the regulation of neurotransmitter release and neurotransmission. CANP10-2 has been shown to play a role in the regulation of dopamine release, a neurotransmitter that is involved in mood, motivation, and pleasure.

CANP10 is also involved in the regulation of cell death, which is the process by which cells die and are removed from the body. It is thought that CANP10 may be involved in the regulation of cell death by promoting the clearance of damaged or dysfunctional cells.

One of the potential benefits of targeting CANP10 is that it has been shown to be involved in the development of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and neurodegenerative disorders. By targeting CANP10 with small molecules, it may be possible to treat these disorders and improve the quality of life for those affected.

Another potential benefit of targeting CANP10 is that it is a relatively small protein, which means that it is relatively easy to synthesize and store. This may make it easier to develop and implement treatments.

In conclusion, CAPN10 (CANP 10) is a protein that is expressed in the brain and is involved in the regulation of cell death. It is a potential drug target (or biomarker) that can be targeted with small molecules to treat various neurological disorders. Further research is needed to fully understand the role of CANP10 in the regulation of cell death and to develop effective treatments.

Protein Name: Calpain 10

Functions: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake

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