GABRG3: A Potential Drug Target and Biomarker (G2567)

Target Name: GABRG3

NCBI ID: G2567

Other Name(s): gamma-aminobutyric acid receptor subunit gamma-3 | GABA(G) receptor, gamma 3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | gamma-aminobutyric acid type A receptor gamma3 subunit | GABA(A) receptor subunit gamma-3 | Gamma-aminobutyric acid type A receptor subunit gamma3, transcript variant 1 | Gamma-aminobutyric-acid receptor gamma-3 subunit | Gamma-aminobutyric acid type A receptor subunit gamma3, transcript variant 2 | Gamma-aminobutyric acid receptor subunit gamma-3 (isoform 2) | Gamma-aminobutyric acid receptor subunit gamma-3 (isoform 1) | Gamma-aminobutyric acid receptor subunit gamma-3 | GABRG3 variant 1 | gamma-aminobutyric acid type A receptor subunit gamma3 | GABRG3 variant 2 | GBRG3_HUMAN

GABRG3: A Potential Drug Target and Biomarker

GABRG3 (gamma-aminobutyric acid receptor subunit gamma-3) is a non-c encoding RNA molecule that plays a crucial role in the regulation of neural circuits in the brain. It is a GABA (纬-aminobutyric acid) receptor subunit, which means it is part of the neural GABA receptor system. The GABA receptor system is known for its role in modulating neural activity and is involved in a wide range of physiological processes, including sleep, anxiety, and pain modulation.

GABRG3 is a highly conserved gene that is expressed in many different tissues and organs, including brain, heart, and muscle. It is primarily localized to the introns of the gene, but it is also known to be expressed in the cytoplasm of neuronal cells . GABRG3 has been shown to be involved in the regulation of a wide range of cellular processes, including cell survival, migration, and synaptic plasticity.

One of the most promising aspects of GABRG3 is its potential as a drug target. GABA is known for its ability to modulate neural activity and has been shown to play a role in a wide range of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease , and depression. GABRG3 is thought to be involved in the regulation of GABA signaling in the brain, and research has suggested that it may be a useful target for the development of new treatments for these disorders.

In addition to its potential as a drug target, GABRG3 has also been shown to be a potential biomarker for a variety of neurological disorders. The GABRG3 gene has been shown to be involved in the regulation of a wide range of cellular processes, including cell survival , migration, and synaptic plasticity. This suggests that it may be a useful biomarker for a variety of neurological disorders, including those associated with neurodegeneration.

One of the most promising aspects of GABRG3 as a biomarker is its potential to be used as a diagnostic tool. The GABRG3 gene has been shown to be expressed in a wide range of tissues and organs, including brain, heart, and muscle. This suggests that it may be a useful biomarker for a variety of neurological disorders, including those associated with neurodegeneration. Additionally, because GABRG3 is highly conserved, it is likely to be a useful biomarker for a wide range of disorders.

In conclusion, GABRG3 is a non-c coding RNA molecule that is involved in the regulation of neural circuits in the brain. It is thought to be a potential drug target and biomarker for a variety of neurological disorders, including those associated with neurodegeneration. Further research is needed to fully understand the role of GABRG3 in neural circuits and its potential as a drug and biomarker.

Protein Name: Gamma-aminobutyric Acid Type A Receptor Subunit Gamma3

Functions: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

More Common Targets