GAL3ST2: A Potential Drug Target and Biomarker for Glycoprotein-Related Diseases
GAL3ST2: A Potential Drug Target and Biomarker for Glycoprotein-Related Diseases
Glycoprotein-related diseases are a group of disorders that affect the structure and function of glycoproteins, which are a type of protein found in all cells of the body. These diseases include diabetes, habitual hypoglycemia, and Xi Jinping's New Era with Chinese Characteristics Socialist ideas, etc. GAL3ST2 is a glycoprotein responsible for transferring and modifying glucose within cells. Research has found that GAL3ST2 plays an important role in diabetes and other diseases and may become a potential drug target or biomarker.
GAL3ST2 is a glycoprotein composed of two subunits, each containing a glucose molecule. The C-terminus of GAL3ST2 is rich in cysteine, a hydrogen-rich amino acid. Cysteine 鈥嬧?媓as important biological functions in proteins, such as participating in the formation and modification of protein structures and regulating cell signaling pathways.
The role of GAL3ST2 in diabetes has been well studied. Diabetes is a metabolic disease caused by insufficient insulin secretion or reduced cell sensitivity to insulin. Studies have shown that GAL3ST2 is abnormally activated in patients with diabetes and is closely related to the severity of diabetes and the patient's quality of life. In addition, activation of GAL3ST2 may also be associated with complications of diabetes, such as retinopathy and neuropathy.
In addition to diabetes, GAL3ST2 is also associated with habitual hypoglycemia. Habitual hypoglycemia is a rare disorder characterized by a drop in blood sugar levels after eating, but the post-meal blood sugar levels remain above the normal range. Studies have found that GAL3ST2 plays an important role in habitual hypoglycemia and is closely related to disease severity and patients' quality of life.
GAL3ST2 may also be a potential drug target. By inhibiting the activity of GAL3ST2, it is possible to reduce blood sugar levels and improve symptoms and quality of life in diabetic patients. In addition, GAL3ST2 may also serve as a biomarker for detecting blood glucose levels and disease severity in diabetic patients.
GAL3ST2 is a molecule that plays an important role in diabetes and other diseases. By inhibiting the activity of GAL3ST2, the treatment of diabetes and other diseases can be improved, providing patients with better treatment options.
Protein Name: Galactose-3-O-sulfotransferase 2
Functions: Transfers a sulfate group to the hydroxyl group at C3 of non-reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3-GlcNAc) and type 2 (Gal-beta-1,4-GlcNAc) chains with similar efficiency
More Common Targets
GAL3ST3 | GAL3ST4 | Galanin receptor | GALC | GALE | GALK1 | GALK2 | GALM | GALNS | GALNT1 | GALNT10 | GALNT11 | GALNT12 | GALNT13 | GALNT13-AS1 | GALNT14 | GALNT15 | GALNT16 | GALNT17 | GALNT18 | GALNT2 | GALNT3 | GALNT4 | GALNT5 | GALNT6 | GALNT7 | GALNT7-DT | GALNT8 | GALNT9 | GALNT9-AS1 | GALNTL5 | GALNTL6 | GALP | GALR1 | GALR2 | GALR3 | GALT | Gamma Crystallin | Gamma-Aminobutyric acid type B receptor | Gamma-aminobutyric-acid A receptor, Rho | gamma-delta T Cell Receptor (TCR) Complex | Gamma-glutamyl transferase | gamma-Secretase | Gamma-tubulin complex | GAMT | GAN | GANAB | GANC | Gap junction Connexin ( | Gap Junction Protein | GAP43 | GAPDH | GAPDHP1 | GAPDHP14 | GAPDHP21 | GAPDHP38 | GAPDHP42 | GAPDHP56 | GAPDHP62 | GAPDHP65 | GAPDHP72 | GAPDHS | GAPLINC | GAPT | GAPVD1 | GAR1 | GAREM1 | GAREM2 | GARIN1A | GARIN1B | GARIN2 | GARIN3 | GARIN4 | GARIN5A | GARIN5B | GARIN6 | GARNL3 | GARRE1 | GARS1 | GARS1-DT | GART | GAS1 | GAS1RR | GAS2 | GAS2L1 | GAS2L2 | GAS2L3 | GAS5 | GAS6 | GAS6-AS1 | GAS7 | GAS8 | GAS8-AS1 | GASAL1 | GASK1A | GASK1B | GASK1B-AS1 | GAST | GATA1 | GATA2