Target Name: GAS6
NCBI ID: G2621
Other Name(s): GAS-6 | AXLLG | AXL receptor tyrosine kinase ligand | Growth arrest specific 6 | AXL stimulatory factor | AXSF | growth arrest specific 6 | GAS6_HUMAN | Growth arrest-specific protein 6

GAS6: A Protein Involved in Tissue Development and Maintenance

GAS6 (GAS-6) is a protein that is expressed in various tissues of the body, including the brain, lungs, heart, kidneys, and intestines. Its name comes from its gene sequence GAS6, which stands for GAS6 gene.

GAS6 is a member of the GAS family of proteins, which are involved in various cellular processes, including cell signaling, DNA replication, and stress response. GAS6 is specifically involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs.

GAS6 is a 21-kDa protein that is expressed in a variety of tissues, including the brain, lungs, heart, kidneys, and intestines. It is primarily localized to the cytoplasm of cells, where it can interact with various cellular signaling pathways.

One of the well-known functions of GAS6 is its role in cell adhesion. GAS6 is involved in the regulation of cell-cell adhesion by creating a complex with a protein called N-cadherin. This complex helps to maintain the integrity of the intercellular space and is critical for the development and maintenance of tissues and organs.

In addition to its role in cell adhesion, GAS6 is also involved in various signaling pathways. For example, GAS6 can interact with the protein PDGF-BB, which is involved in cell signaling and growth. This interaction between GAS6 and PDGF-BB may be important for the regulation of cell growth and differentiation.

GAS6 has also been shown to play a role in the regulation of inflammation. For example, GAS6 can interact with the protein NF-kappa-B, which is involved in the regulation of inflammation and immune response. This interaction between GAS6 and NF-kappa-B may be important for the regulation of inflammatory responses.

GAS6 is also involved in the regulation of cell cycle progression. For example, GAS6 can interact with the protein cyclin D1, which is involved in the regulation of cell cycle progression. This interaction between GAS6 and cyclin D1 may be important for the regulation of cell proliferation and the completion of cell cycles.

GAS6 is also involved in the regulation of cellular signaling pathways that are important for the development and maintenance of tissues and organs. For example, GAS6 can interact with the protein TGF-β, which is involved in the regulation of cell signaling pathways that are important. for the development and maintenance of tissues and organs. This interaction between GAS6 and TGF-β may be important for the regulation of cell signaling pathways that are important for tissue development and maintenance.

In conclusion, GAS6 is a protein that is involved in various cellular processes that are important for the development and maintenance of tissues and organs. Its role in cell adhesion, signaling pathways, and inflammation may be important for the regulation of cellular processes that are critical for tissue development and maintenance. As a potential drug target or biomarker, GAS6 may be a useful target for the development of new therapies for various diseases.

Protein Name: Growth Arrest Specific 6

Functions: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses

More Common Targets

GAS6-AS1 | GAS7 | GAS8 | GAS8-AS1 | GASAL1 | GASK1A | GASK1B | GASK1B-AS1 | GAST | GATA1 | GATA2 | GATA2-AS1 | GATA3 | GATA3-AS1 | GATA4 | GATA5 | GATA6 | GATA6-AS1 | GATAD1 | GATAD2A | GATAD2B | GATB | GATC | GATD1 | GATD1-DT | GATD3 | GATM | GATOR1 Complex | GAU1 | GBA1 | GBA2 | GBA3 | GBAP1 | GBE1 | GBF1 | GBGT1 | GBP1 | GBP1P1 | GBP2 | GBP3 | GBP4 | GBP5 | GBP6 | GBP7 | GBX1 | GBX2 | GC | GCA | GCAT | GCC1 | GCC2 | GCC2-AS1 | GCDH | GCFC2 | GCG | GCGR | GCH1 | GCHFR | GCK | GCKR | GCLC | GCLM | GCM1 | GCM2 | GCN1 | GCNA | GCNT1 | GCNT1P3 | GCNT2 | GCNT3 | GCNT4 | GCNT7 | GCOM1 | GCSAM | GCSAML | GCSAML-AS1 | GCSH | GCSHP3 | GCSIR | GDA | GDAP1 | GDAP1L1 | GDAP2 | GDE1 | GDF1 | GDF10 | GDF11 | GDF15 | GDF2 | GDF3 | GDF5 | GDF6 | GDF7 | GDF9 | GDI1 | GDI2 | GDI2P1 | GDNF | GDNF Family Receptor alpha | GDNF-AS1