Understanding The Role of GAPVD1 in Cell Signaling Pathways and Cytoskeleton

Target Name: GAPVD1

NCBI ID: G26130

Understanding The Role of GAPVD1 in Cell Signaling Pathways and Cytoskeleton

GAPVD1, also known as GTPase activating protein and VPS9 domains 1, transcript variant 4, is a protein that plays a critical role in various cellular processes. It is a protein that is expressed in most tissues of the body and is known to be involved in the regulation of cell signaling pathways. GAPVD1 is a protein that can modulate the activity of various proteins, including GTPases. GAPVD1 is also known to be involved in the regulation of the actinin cytoskeleton and has been shown to play a role in the regulation of cell migration.

GAPVD1 is a protein that is composed of several domains, including a GAP domain, a VPS9 domain, and a unique N-terminal domain. The GAP domain is a protein that is known to be involved in the regulation of protein-protein interactions and is thought to play a role in the regulation of GAPVD1 function. The VPS9 domain is a protein that is known to be involved in the regulation of protein stability and is also thought to play a role in the regulation of GAPVD1 function. The N-terminal domain is a protein that is known to be involved in the regulation of protein stability and is also thought to play a role in the regulation of GAPVD1 function.

GAPVD1 has been shown to play a role in the regulation of a variety of cellular processes, including cell signaling pathways, cytoskeleton regulation, and cell migration. For example, GAPVD1 has been shown to play a role in the regulation of the PI3K/AKT signaling pathway, a pathway that is involved in the regulation of cellular signaling pathways. GAPVD1 has also been shown to play a role in the regulation of the NF-kappa-B signaling pathway, a pathway that is involved in the regulation of cellular signaling pathways.

In addition to its role in cellular signaling pathways, GAPVD1 is also known to be involved in the regulation of cytoskeleton structure and function. For example, GAPVD1 has been shown to play a role in the regulation of actinin cytoskeleton stability and has been shown to contribute to the regulation of cell migration.

GAPVD1 is also known to be involved in the regulation of protein stability. For example, GAPVD1 has been shown to play a role in the regulation of protein stability and has been shown to contribute to the regulation of protein stability in cells.

GAPVD1 is a protein that is known to play a critical role in various cellular processes and is involved in the regulation of cell signaling pathways, cytoskeleton structure and function, and protein stability. As a result, GAPVD1 is a protein that may be a drug target or biomarker. Further research is needed to fully understand the function of GAPVD1 and its potential as a drug or biomarker.

Protein Name: GTPase Activating Protein And VPS9 Domains 1

Functions: Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. Acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside the cells. Upon insulin stimulation, it is translocated to the plasma membrane, releasing LC2A4/GLUT4 from intracellular storage vesicles. Also involved in EGFR trafficking and degradation, possibly by promoting EGFR ubiquitination and subsequent degradation by the proteasome. Has GEF activity for Rab5 and GAP activity for Ras

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