GAS5: A Potential Drug Target and Biomarker (G60674)
GAS5: A Potential Drug Target and Biomarker
GAS5, also known as Growth Arrest-Specific 5, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell growth and has been identified as a potential drug target in the treatment of various diseases, including cancer.
The discovery of GAS5 comes from a study by researchers at the University of California, San Diego, who used techniques such as RNA interference and live cell imaging to show that GAS5 was highly expressed in various tissues, including the brain, heart, and liver. They also found that GAS5 was involved in the regulation of cell growth, and that inhibiting its activity could lead to a reduction in cell proliferation.
GAS5 is also known as PDGF-BB, which stands for platelet-derived growth factor-B. This protein is involved in the regulation of cell growth, cell differentiation, and angiogenesis, which is the formation of new blood vessels.
GAS5 has been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of GAS5 are associated with poor prognosis in patients with pancreatic cancer, and that inhibiting its activity may be a promising approach to treating this disease.
In addition to its potential as a drug target, GAS5 has also been shown to have potential as a biomarker. Its expression has been detected in various tissues and has been shown to be associated with the development of certain diseases, such as cancer. This suggests that GAS5 may be a useful indicator of disease status, and that its levels may be able to be used to inform decisions about diagnosis and treatment.
GAS5 is also a good candidate for a diagnostic biomarker, as its expression can be detected using techniques such as qRT-PCR, a widely used method for detecting RNA in biological samples. This suggests that GAS5 may be a useful diagnostic tool for the detection of various diseases, including cancer.
In conclusion, GAS5 is a protein that has been identified as a potential drug target and biomarker. Its expression is involved in the regulation of cell growth and has been shown to be involved in the development and progression of various diseases, including cancer. Further research is needed to fully understand its potential as a drug and diagnostic biomarker.
Protein Name: Growth Arrest Specific 5
More Common Targets
GAS6 | GAS6-AS1 | GAS7 | GAS8 | GAS8-AS1 | GASAL1 | GASK1A | GASK1B | GASK1B-AS1 | GAST | GATA1 | GATA2 | GATA2-AS1 | GATA3 | GATA3-AS1 | GATA4 | GATA5 | GATA6 | GATA6-AS1 | GATAD1 | GATAD2A | GATAD2B | GATB | GATC | GATD1 | GATD1-DT | GATD3 | GATM | GATOR1 Complex | GAU1 | GBA1 | GBA2 | GBA3 | GBAP1 | GBE1 | GBF1 | GBGT1 | GBP1 | GBP1P1 | GBP2 | GBP3 | GBP4 | GBP5 | GBP6 | GBP7 | GBX1 | GBX2 | GC | GCA | GCAT | GCC1 | GCC2 | GCC2-AS1 | GCDH | GCFC2 | GCG | GCGR | GCH1 | GCHFR | GCK | GCKR | GCLC | GCLM | GCM1 | GCM2 | GCN1 | GCNA | GCNT1 | GCNT1P3 | GCNT2 | GCNT3 | GCNT4 | GCNT7 | GCOM1 | GCSAM | GCSAML | GCSAML-AS1 | GCSH | GCSHP3 | GCSIR | GDA | GDAP1 | GDAP1L1 | GDAP2 | GDE1 | GDF1 | GDF10 | GDF11 | GDF15 | GDF2 | GDF3 | GDF5 | GDF6 | GDF7 | GDF9 | GDI1 | GDI2 | GDI2P1 | GDNF | GDNF Family Receptor alpha
